tetano
Editor, Senior Moderator
J Cardiovasc Echogr
. 2024 Apr-Jun;34(2):72-76.
doi: 10.4103/jcecho.jcecho_3_24. Epub 2024 Jun 28. Echocardiographic Assessment of Recovered Patients with Mild COVID-19 Infection: A Case-Control Study
Hedieh Alimi[SUP] 1 [/SUP], Leila Bigdelu[SUP] 1 [/SUP], Hoorak Poorzand[SUP] 1 [/SUP], Fereshteh Ghaderi[SUP] 1 [/SUP], Maryam Emadzadeh[SUP] 2 [/SUP], Asal Yadollahi[SUP] 3 [/SUP], Azadeh Izadi-Moud[SUP] 3 [/SUP], Afsoon Fazlinezhad[SUP] 1 [/SUP], Maedeh Rezaei Danesh[SUP] 3 [/SUP]
Affiliations
Context: Coronavirus disease 2019 (COVID-19) has been revealed as a severe illness with a wide-ranging cardiac manifestation and has a worldwide burden on the health-care system.
Aims: Our aim in this study is to assess the impact of mild COVID-19 infection on cardiac function in patients without previous structural heart disease.
Settings and design: We evaluated 100 outpatients with a history of mild COVID-19 infection without needing hospitalization within 3 weeks to 3 months after recovery from the acute phase of the illness between August 2020 and July 2021.
Subjects and methods: The patients were compared with 105 healthy participants without a history of COVID-19 as the control group. All participants underwent comprehensive transthoracic echocardiography.
Statistical analysis used: Data were analyzed using IBM SPSS statistics 23. For all tests, P < 0.05 was defined as statistically significant.
Results: COVID-19 patients had higher global longitudinal strain (P = 0.001), systolic pulmonary artery pressure (P = 0.008), RV E' (P = 0.049), and RV A' (P = 0.003), while had lower septal tissue velocities (P = 0.01) and left ventricular ejection fraction (EF) (LVEF) (P = 0.03). Abnormal EF (LVEF <55%) was noted in 19% of the COVID-19 patients and 8.6% of the control group (P = 0.03). Moderate or more diastolic dysfunction was noted in 10 COVID-19 patients but only in one participant in the control group (P = 0.005).
Conclusions: Mild COVID-19 infection can result in cardiac functional and structural changes, even in patients without known previous structural heart disease. Echocardiography can be a useful modality for risk assessment and follow-up in patients with COVID-19.
Keywords: Coronavirus disease 2019; echocardiography; left ventricular ejection fraction; left ventricular strain; systolic pulmonary artery pressure.
. 2024 Apr-Jun;34(2):72-76.
doi: 10.4103/jcecho.jcecho_3_24. Epub 2024 Jun 28. Echocardiographic Assessment of Recovered Patients with Mild COVID-19 Infection: A Case-Control Study
Hedieh Alimi[SUP] 1 [/SUP], Leila Bigdelu[SUP] 1 [/SUP], Hoorak Poorzand[SUP] 1 [/SUP], Fereshteh Ghaderi[SUP] 1 [/SUP], Maryam Emadzadeh[SUP] 2 [/SUP], Asal Yadollahi[SUP] 3 [/SUP], Azadeh Izadi-Moud[SUP] 3 [/SUP], Afsoon Fazlinezhad[SUP] 1 [/SUP], Maedeh Rezaei Danesh[SUP] 3 [/SUP]
Affiliations
- PMID: 39086699
- PMCID: PMC11288305
- DOI: 10.4103/jcecho.jcecho_3_24
Context: Coronavirus disease 2019 (COVID-19) has been revealed as a severe illness with a wide-ranging cardiac manifestation and has a worldwide burden on the health-care system.
Aims: Our aim in this study is to assess the impact of mild COVID-19 infection on cardiac function in patients without previous structural heart disease.
Settings and design: We evaluated 100 outpatients with a history of mild COVID-19 infection without needing hospitalization within 3 weeks to 3 months after recovery from the acute phase of the illness between August 2020 and July 2021.
Subjects and methods: The patients were compared with 105 healthy participants without a history of COVID-19 as the control group. All participants underwent comprehensive transthoracic echocardiography.
Statistical analysis used: Data were analyzed using IBM SPSS statistics 23. For all tests, P < 0.05 was defined as statistically significant.
Results: COVID-19 patients had higher global longitudinal strain (P = 0.001), systolic pulmonary artery pressure (P = 0.008), RV E' (P = 0.049), and RV A' (P = 0.003), while had lower septal tissue velocities (P = 0.01) and left ventricular ejection fraction (EF) (LVEF) (P = 0.03). Abnormal EF (LVEF <55%) was noted in 19% of the COVID-19 patients and 8.6% of the control group (P = 0.03). Moderate or more diastolic dysfunction was noted in 10 COVID-19 patients but only in one participant in the control group (P = 0.005).
Conclusions: Mild COVID-19 infection can result in cardiac functional and structural changes, even in patients without known previous structural heart disease. Echocardiography can be a useful modality for risk assessment and follow-up in patients with COVID-19.
Keywords: Coronavirus disease 2019; echocardiography; left ventricular ejection fraction; left ventricular strain; systolic pulmonary artery pressure.