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J Clin Med . Comparison of the Characteristics and Outcomes of COVID-19 Patients Treated by a Hospital-at-Home Service in Japan during the Alpha an

tetano

Editor, Senior Moderator
J Clin Med


. 2022 Jun 2;11(11):3185.
doi: 10.3390/jcm11113185.
Comparison of the Characteristics and Outcomes of COVID-19 Patients Treated by a Hospital-at-Home Service in Japan during the Alpha and Delta Waves


Ryota Inokuchi[SUP] 1 2 [/SUP], Xueying Jin[SUP] 1 2 [/SUP], Masao Iwagami[SUP] 1 2 [/SUP], Yu Sun[SUP] 3 [/SUP], Ayaka Sakamoto[SUP] 3 [/SUP], Masatoshi Ishikawa[SUP] 1 2 [/SUP], Nanako Tamiya[SUP] 1 2 [/SUP]



Affiliations

Abstract

Coronavirus infections occurred in repeated waves caused by different variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with the number of patients increasing during each wave. A private after-hours house-call (AHHC) service provides hospital-at-home (HaH) services to patients in Japan requiring oxygen when hospital beds are in short supply. This retrospective study aimed to compare the characteristics of COVID-19 patients treated by the AHHC service during the COVID-19 waves caused by the Alpha (March-June 2021) and Delta (July-December 2021) SARS-CoV-2 variants. All patients with COVID-19 treated by the AHHC service from March to December 2021 while awaiting hospitalization were included. The data were collected from medical records and follow-up telephone interviews. The AHHC service treated 55 and 273 COVID-19 patients during the Alpha and Delta waves, respectively. The patients treated during the Delta wave were significantly younger than those treated during the Alpha wave (median: 63 years and 47 years, respectively; p < 0.001). Disease severity did not differ significantly between the two waves, but the crude case-fatality rate was significantly higher during the Alpha wave (10/55, 18.2%) than during the Delta wave (4/273, 1.4%; p < 0.001). The patient characteristics and outcomes differed between the Alpha and Delta waves.

Keywords: after-hours house-call medical service; emergency department; out-of-hours services; public health center.
 
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