tetano
Editor, Senior Moderator
J Clin Med
. 2020 May 31;9(6):E1651.
doi: 10.3390/jcm9061651.
COVID-19 Related Coagulopathy: A Distinct Entity?
Benjamin Marchandot[SUP] 1 [/SUP], Laurent Sattler[SUP] 2 [/SUP], Laurence Jesel[SUP] 1 3 [/SUP], Kensuke Matsushita[SUP] 1 3 [/SUP], Valerie Schini-Kerth[SUP] 3 [/SUP], Lelia Grunebaum[SUP] 2 [/SUP], Olivier Morel[SUP] 1 3 [/SUP]
Affiliations
Abstract
The coronavirus disease 2019 (COVID-19) pandemic has impacted healthcare communities across the globe on an unprecedented scale. Patients have had diverse clinical outcomes, but those developing COVID-19-related coagulopathy have shown a disproportionately worse outcome. This narrative review summarizes current evidence regarding the epidemiology, clinical features, known and presumed pathophysiology-based models, and treatment guidance regarding COVID-19 coagulopathy.
Keywords: COVID-19; antiphospholipid antibodies; coronavirus disease 2019; endothelium; hemostasis; microparticles; thrombosis.
. 2020 May 31;9(6):E1651.
doi: 10.3390/jcm9061651.
COVID-19 Related Coagulopathy: A Distinct Entity?
Benjamin Marchandot[SUP] 1 [/SUP], Laurent Sattler[SUP] 2 [/SUP], Laurence Jesel[SUP] 1 3 [/SUP], Kensuke Matsushita[SUP] 1 3 [/SUP], Valerie Schini-Kerth[SUP] 3 [/SUP], Lelia Grunebaum[SUP] 2 [/SUP], Olivier Morel[SUP] 1 3 [/SUP]
Affiliations
- PMID: 32486469
- DOI: 10.3390/jcm9061651
Abstract
The coronavirus disease 2019 (COVID-19) pandemic has impacted healthcare communities across the globe on an unprecedented scale. Patients have had diverse clinical outcomes, but those developing COVID-19-related coagulopathy have shown a disproportionately worse outcome. This narrative review summarizes current evidence regarding the epidemiology, clinical features, known and presumed pathophysiology-based models, and treatment guidance regarding COVID-19 coagulopathy.
Keywords: COVID-19; antiphospholipid antibodies; coronavirus disease 2019; endothelium; hemostasis; microparticles; thrombosis.