tetano
Editor, Senior Moderator
J Clin Med
. 2023 Aug 15;12(16):5304.
doi: 10.3390/jcm12165304. Indirect Effects of the COVID-19 Pandemic on In-Hospital Outcomes among Internal Medicine Departments: A Double-Center Retrospective Study
Maurizio Di Marco[SUP] 1 [/SUP], Nicoletta Miano[SUP] 1 [/SUP], Simona Marchisello[SUP] 1 [/SUP], Giuseppe Coppolino[SUP] 1 [/SUP], Giuseppe L'Episcopo[SUP] 1 [/SUP], Sabrina Scilletta[SUP] 1 [/SUP], Concetta Spichetti[SUP] 1 [/SUP], Serena Torre[SUP] 1 [/SUP], Roberto Scicali[SUP] 1 [/SUP], Luca Zanoli[SUP] 1 [/SUP], Agostino Gaudio[SUP] 1 [/SUP], Pietro Castellino[SUP] 1 [/SUP], Salvatore Piro[SUP] 1 [/SUP], Francesco Purrello[SUP] 1 [/SUP], Antonino Di Pino[SUP] 1 [/SUP]
Affiliations
The coronavirus disease 19 (COVID-19) emergency led to rearrangements of healthcare systems with a significant impact on those internal medicine departments that had not been converted to COVID-19 wards. A reduced number of departments, indeed, had to cope with the same number of patients along with a lack of management of patients' chronic diseases. We conducted a retrospective study aimed at examiningthe consequences of the COVID-19 pandemic on internal medicine departments that were not directly managing COVID-19 patients. Data from 619 patients were collected: 247 subjects hospitalized in 2019 (pre-COVID-19 era), 178 in 2020 (COVID-19 outbreak era) and 194 in 2021 (COVID-19 ongoing era). We found that in 2020 in-hospital mortality was significantly higher than in 2019 (17.4% vs. 5.3%, p = 0.009) as well as length of in-hospital stay (LOS) (12.7 ± 6.8 vs. 11 ± 6.2, p = 0.04). Finally, we performed a logistic regression analysis of the major determinants of mortality in the entire study population, which highlighted an association between mortality, being bedridden (β = 1.4, p = 0.004), respiratory failure (β = 1.5, p = 0.001), glomerular filtration rate (β = -0.16, p = 0.03) and hospitalization in the COVID-19 outbreak era (β = 1.6, p = 0.005). Our study highlights how the COVID-19 epidemic may have caused an increase in mortality and LOS even in patients not directly suffering from this infection.
Keywords: COVID-19; in-hospital mortality; in-hospital outcomes; internal medicine departments; length of in-hospital stay; sepsis.
. 2023 Aug 15;12(16):5304.
doi: 10.3390/jcm12165304. Indirect Effects of the COVID-19 Pandemic on In-Hospital Outcomes among Internal Medicine Departments: A Double-Center Retrospective Study
Maurizio Di Marco[SUP] 1 [/SUP], Nicoletta Miano[SUP] 1 [/SUP], Simona Marchisello[SUP] 1 [/SUP], Giuseppe Coppolino[SUP] 1 [/SUP], Giuseppe L'Episcopo[SUP] 1 [/SUP], Sabrina Scilletta[SUP] 1 [/SUP], Concetta Spichetti[SUP] 1 [/SUP], Serena Torre[SUP] 1 [/SUP], Roberto Scicali[SUP] 1 [/SUP], Luca Zanoli[SUP] 1 [/SUP], Agostino Gaudio[SUP] 1 [/SUP], Pietro Castellino[SUP] 1 [/SUP], Salvatore Piro[SUP] 1 [/SUP], Francesco Purrello[SUP] 1 [/SUP], Antonino Di Pino[SUP] 1 [/SUP]
Affiliations
- PMID: 37629346
- PMCID: PMC10455112
- DOI: 10.3390/jcm12165304
The coronavirus disease 19 (COVID-19) emergency led to rearrangements of healthcare systems with a significant impact on those internal medicine departments that had not been converted to COVID-19 wards. A reduced number of departments, indeed, had to cope with the same number of patients along with a lack of management of patients' chronic diseases. We conducted a retrospective study aimed at examiningthe consequences of the COVID-19 pandemic on internal medicine departments that were not directly managing COVID-19 patients. Data from 619 patients were collected: 247 subjects hospitalized in 2019 (pre-COVID-19 era), 178 in 2020 (COVID-19 outbreak era) and 194 in 2021 (COVID-19 ongoing era). We found that in 2020 in-hospital mortality was significantly higher than in 2019 (17.4% vs. 5.3%, p = 0.009) as well as length of in-hospital stay (LOS) (12.7 ± 6.8 vs. 11 ± 6.2, p = 0.04). Finally, we performed a logistic regression analysis of the major determinants of mortality in the entire study population, which highlighted an association between mortality, being bedridden (β = 1.4, p = 0.004), respiratory failure (β = 1.5, p = 0.001), glomerular filtration rate (β = -0.16, p = 0.03) and hospitalization in the COVID-19 outbreak era (β = 1.6, p = 0.005). Our study highlights how the COVID-19 epidemic may have caused an increase in mortality and LOS even in patients not directly suffering from this infection.
Keywords: COVID-19; in-hospital mortality; in-hospital outcomes; internal medicine departments; length of in-hospital stay; sepsis.