tetano
Editor, Senior Moderator
J Clin Med
. 2023 Apr 18;12(8):2925.
doi: 10.3390/jcm12082925. Long-Term Mortality after New-Onset Atrial Fibrillation in COVID-19
Stjepan Jurisic[SUP] 1 2 [/SUP], Mathis Komminoth[SUP] 1 [/SUP], Atanas Todorov[SUP] 3 [/SUP], Daniela A Bertschi[SUP] 1 [/SUP], Martin Jurisic[SUP] 4 [/SUP], Ivica Vranjic[SUP] 1 [/SUP], Benedikt Wiggli[SUP] 5 [/SUP], Hansruedi Schmid[SUP] 1 [/SUP], Catherine Gebhard[SUP] 1 3 6 [/SUP], Caroline E Gebhard[SUP] 7 [/SUP], Bettina Heidecker[SUP] 8 [/SUP], Jürg-Hans Beer[SUP] 1 6 [/SUP], Dimitri Patriki[SUP] 1 2 [/SUP]
Affiliations
Background: Atrial fibrillation (AF) has been described as a common cardiovascular manifestation in patients suffering from coronavirus disease 2019 (COVID-19) and has been suggested to be a potential risk factor for a poor clinical outcome. Methods: In this observational study, all patients hospitalized due to COVID-19 in 2020 in the Cantonal Hospital of Baden were included. We assessed clinical characteristics, in-hospital outcomes as well as long-term outcomes with a mean follow-up time of 278 (±90) days. Results: Amongst 646 patients diagnosed with COVID-19 (59% male, median age: 70 (IQR: 59-80)) in 2020, a total of 177 (27.4%) patients were transferred to the intermediate/intensive care unit (IMC/ICU), and 76 (11.8%) were invasively ventilated during their hospitalization. Ninety patients (13.9%) died. A total of 116 patients (18%) showed AF on admission of which 34 (29%) had new-onset AF. Patients with COVID-19 and newly diagnosed AF were more likely to require invasive ventilation (OR: 3.5; p = 0.01) but did not encounter an increased in-hospital mortality. Moreover, AF neither increased long-term mortality nor the number of rehospitalizations during follow-up after adjusting for confounders. Conclusions: In patients suffering from COVID-19, the new-onset of AF on admission was associated with an increased risk of invasive ventilation and transfer to the IMC/ICU but did not affect in-hospital or long-term mortality.
Keywords: COVID-19; atrial fibrillation; outcome.
. 2023 Apr 18;12(8):2925.
doi: 10.3390/jcm12082925. Long-Term Mortality after New-Onset Atrial Fibrillation in COVID-19
Stjepan Jurisic[SUP] 1 2 [/SUP], Mathis Komminoth[SUP] 1 [/SUP], Atanas Todorov[SUP] 3 [/SUP], Daniela A Bertschi[SUP] 1 [/SUP], Martin Jurisic[SUP] 4 [/SUP], Ivica Vranjic[SUP] 1 [/SUP], Benedikt Wiggli[SUP] 5 [/SUP], Hansruedi Schmid[SUP] 1 [/SUP], Catherine Gebhard[SUP] 1 3 6 [/SUP], Caroline E Gebhard[SUP] 7 [/SUP], Bettina Heidecker[SUP] 8 [/SUP], Jürg-Hans Beer[SUP] 1 6 [/SUP], Dimitri Patriki[SUP] 1 2 [/SUP]
Affiliations
- PMID: 37109261
- DOI: 10.3390/jcm12082925
Background: Atrial fibrillation (AF) has been described as a common cardiovascular manifestation in patients suffering from coronavirus disease 2019 (COVID-19) and has been suggested to be a potential risk factor for a poor clinical outcome. Methods: In this observational study, all patients hospitalized due to COVID-19 in 2020 in the Cantonal Hospital of Baden were included. We assessed clinical characteristics, in-hospital outcomes as well as long-term outcomes with a mean follow-up time of 278 (±90) days. Results: Amongst 646 patients diagnosed with COVID-19 (59% male, median age: 70 (IQR: 59-80)) in 2020, a total of 177 (27.4%) patients were transferred to the intermediate/intensive care unit (IMC/ICU), and 76 (11.8%) were invasively ventilated during their hospitalization. Ninety patients (13.9%) died. A total of 116 patients (18%) showed AF on admission of which 34 (29%) had new-onset AF. Patients with COVID-19 and newly diagnosed AF were more likely to require invasive ventilation (OR: 3.5; p = 0.01) but did not encounter an increased in-hospital mortality. Moreover, AF neither increased long-term mortality nor the number of rehospitalizations during follow-up after adjusting for confounders. Conclusions: In patients suffering from COVID-19, the new-onset of AF on admission was associated with an increased risk of invasive ventilation and transfer to the IMC/ICU but did not affect in-hospital or long-term mortality.
Keywords: COVID-19; atrial fibrillation; outcome.