tetano
Editor, Senior Moderator
J Clin Med
. 2021 Apr 6;10(7):1539.
doi: 10.3390/jcm10071539.
Physical Activity and the Risk of COVID-19 Infection and Mortality: A Nationwide Population-Based Case-Control Study
Dong-Hyuk Cho[SUP] 1 [/SUP], Sun Ju Lee[SUP] 2 [/SUP], Sae Young Jae[SUP] 3 [/SUP], Woo Joo Kim[SUP] 4 [/SUP], Seong Jun Ha[SUP] 2 [/SUP], Jun Gyo Gwon[SUP] 5 [/SUP], Jimi Choi[SUP] 6 [/SUP], Dong Wook Kim[SUP] 2 [/SUP], Jang Young Kim[SUP] 1 [/SUP]
Affiliations
Abstract
Regular physical activity (PA) is known to reduce the risk of serious community-acquired infections. We examined the association of PA with the morbidity and mortality resulting from coronavirus disease (COVID-19) infection in the South Korean population. Patients who tested positive for severe acute respiratory coronavirus 2 and who underwent public health screening between 2014 and 2017 (n = 6288) were included. Age- and sex-matched controls (n = 125,772) were randomly selected from the Korean National Health Insurance Service database. Leisure-time PA was assessed using a self-reported questionnaire. The mean PA levels were lower in the patient than in the control group (558.2 ? 516.3 vs. 580.2 ? 525.7 metabolic equivalent of task (MET)-min/week, p = 0.001). Patients with moderate to vigorous PA (MVPA) were associated with a lower risk of COVID-19 morbidity (odds ratio (OR), 0.90; 95% confidence interval (CI), 0.86-0.95). In addition, a standard deviation (SD) increment in MET/week (525.3 MET-min/week) was associated with a 4% decrease in the risk of COVID-19 morbidity (OR, 0.96; 95% CI, 0.93-0.99). MVPA and an SD increment in MET/week were associated with lower mortality (MVPA: OR, 0.47; 95% CI, 0.26-0.87; per SD increment: OR, 0.65; 95% CI, 0.48-0.88). Higher levels of regular PA were associated with a lower risk of COVID-19 infection and mortality, highlighting the importance of maintaining appropriate levels of PA along with social distancing amid the COVID-19 pandemic.
Keywords: COVID-19; mortality; physical activity; severe acute respiratory coronavirus 2.
. 2021 Apr 6;10(7):1539.
doi: 10.3390/jcm10071539.
Physical Activity and the Risk of COVID-19 Infection and Mortality: A Nationwide Population-Based Case-Control Study
Dong-Hyuk Cho[SUP] 1 [/SUP], Sun Ju Lee[SUP] 2 [/SUP], Sae Young Jae[SUP] 3 [/SUP], Woo Joo Kim[SUP] 4 [/SUP], Seong Jun Ha[SUP] 2 [/SUP], Jun Gyo Gwon[SUP] 5 [/SUP], Jimi Choi[SUP] 6 [/SUP], Dong Wook Kim[SUP] 2 [/SUP], Jang Young Kim[SUP] 1 [/SUP]
Affiliations
- PMID: 33917558
- DOI: 10.3390/jcm10071539
Abstract
Regular physical activity (PA) is known to reduce the risk of serious community-acquired infections. We examined the association of PA with the morbidity and mortality resulting from coronavirus disease (COVID-19) infection in the South Korean population. Patients who tested positive for severe acute respiratory coronavirus 2 and who underwent public health screening between 2014 and 2017 (n = 6288) were included. Age- and sex-matched controls (n = 125,772) were randomly selected from the Korean National Health Insurance Service database. Leisure-time PA was assessed using a self-reported questionnaire. The mean PA levels were lower in the patient than in the control group (558.2 ? 516.3 vs. 580.2 ? 525.7 metabolic equivalent of task (MET)-min/week, p = 0.001). Patients with moderate to vigorous PA (MVPA) were associated with a lower risk of COVID-19 morbidity (odds ratio (OR), 0.90; 95% confidence interval (CI), 0.86-0.95). In addition, a standard deviation (SD) increment in MET/week (525.3 MET-min/week) was associated with a 4% decrease in the risk of COVID-19 morbidity (OR, 0.96; 95% CI, 0.93-0.99). MVPA and an SD increment in MET/week were associated with lower mortality (MVPA: OR, 0.47; 95% CI, 0.26-0.87; per SD increment: OR, 0.65; 95% CI, 0.48-0.88). Higher levels of regular PA were associated with a lower risk of COVID-19 infection and mortality, highlighting the importance of maintaining appropriate levels of PA along with social distancing amid the COVID-19 pandemic.
Keywords: COVID-19; mortality; physical activity; severe acute respiratory coronavirus 2.