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J Clin Med . Physical Health-Related Quality of Life Improves over Time in Post-COVID-19 Patients: An Exploratory Prospective Study

tetano

Editor, Senior Moderator
J Clin Med


. 2023 Jun 15;12(12):4077.
doi: 10.3390/jcm12124077. Physical Health-Related Quality of Life Improves over Time in Post-COVID-19 Patients: An Exploratory Prospective Study

Stefan Malesevic[SUP] 1 2 [/SUP], Noriane A Sievi[SUP] 2 [/SUP], Dörthe Schmidt[SUP] 3 [/SUP], Florence Vallelian[SUP] 4 [/SUP], Ilijas Jelcic[SUP] 5 [/SUP], Malcolm Kohler[SUP] 2 [/SUP], Christian F Clarenbach[SUP] 2 [/SUP]



Affiliations
Abstract

(1) Background: Ongoing symptoms after mild or moderate acute coronavirus disease 19 (COVID-19) substantially affect health-related quality of life (HRQoL). However, follow-up data on HRQoL are scarce. We characterized the change in HRQoL over time in post-COVID-19 patients who initially suffered from mild or moderate acute COVID-19 without hospitalization. (2) Methods: Outpatients who visited an interdisciplinary post-COVID-19 consultation at the University Hospital Zurich and suffered from ongoing symptoms after acute COVID-19 were included in this observational study. HRQoL was assessed using established questionnaires. Six months after baseline, the same questionnaires and a self-constructed questionnaire about the COVID-19 vaccination were distributed. (3) Results: In total, 69 patients completed the follow-up, of whom 55 (80%) were female. The mean (SD) age was 44 (12) years and the median (IQR) time from symptom onset to completing the follow-up was 326 (300, 391) days. The majority of patients significantly improved in EQ-5D-5L health dimensions of mobility, usual activities, pain and anxiety. Furthermore, according to the SF-36, patients showed clinically relevant improvements in physical health, whereas no significant change was found regarding mental health. (4) Conclusions: Physical aspects of HRQoL in post-COVID-19 patients relevantly improved over 6 months. Future studies are needed to focus on potential predictors that allow for establishing individual care and early interventions.

Keywords: follow-up; health-related quality of life; mental health; physical health; post-COVID-19.

 
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