tetano
Editor, Senior Moderator
J Clin Med
. 2023 Sep 7;12(18):5812.
doi: 10.3390/jcm12185812. Risk Factors for Severe-Critical COVID-19 in Pregnant Women
María Guadalupe Berumen-Lechuga[SUP] 1 [/SUP], Alfredo Leaños-Miranda[SUP] 2 [/SUP], Carlos José Molina-Pérez[SUP] 3 [/SUP], Luis Rey García-Cortes[SUP] 4 [/SUP], Silvia Palomo-Piñón[SUP] 5 [/SUP]
Affiliations
Risk factors associated with severe-critical COVID-19 (coronavirus disease 2019) are based on findings in the general population. Pregnant women are at increased risk of severe-critical infection, and few reports are based on these women. A multicentric case-control study was conducted at the Mexican Institute of Social Security, State of Mexico, during the COVID-19 pandemic. We included pregnant women who were consecutively admitted to respiratory care units and were followed until 30 days after the resolution of pregnancy. A total of 758 pregnant women with a positive RT-PCR test for SARS-CoV-2 were enrolled from June 2020 to July 2021. We defined groups using the World Health Organization Severity Classification; cases were pregnant women with severe-critical COVID-19 (n = 123), and controls were subjects with non-severe COVID-19 (n = 635). Data was gathered from clinical files. A multivariate logistic regression analysis was used to adjust odds ratios and their 95% confidence intervals of factors associated with severe-critical COVID-19. Risk factors associated with severe-critical COVID-19 in pregnancy were non-vaccination (OR 10.18), blood type other than O (OR 6.29), maternal age > 35 years (OR 5.76), history of chronic hypertension (OR 5.12), gestational age at infection ≥ 31 weeks (OR 3.28), and multiparity (OR 2.80).
Keywords: COVID-19; SARS-CoV-2; coronavirus infections; pregnancy.
. 2023 Sep 7;12(18):5812.
doi: 10.3390/jcm12185812. Risk Factors for Severe-Critical COVID-19 in Pregnant Women
María Guadalupe Berumen-Lechuga[SUP] 1 [/SUP], Alfredo Leaños-Miranda[SUP] 2 [/SUP], Carlos José Molina-Pérez[SUP] 3 [/SUP], Luis Rey García-Cortes[SUP] 4 [/SUP], Silvia Palomo-Piñón[SUP] 5 [/SUP]
Affiliations
- PMID: 37762753
- DOI: 10.3390/jcm12185812
Risk factors associated with severe-critical COVID-19 (coronavirus disease 2019) are based on findings in the general population. Pregnant women are at increased risk of severe-critical infection, and few reports are based on these women. A multicentric case-control study was conducted at the Mexican Institute of Social Security, State of Mexico, during the COVID-19 pandemic. We included pregnant women who were consecutively admitted to respiratory care units and were followed until 30 days after the resolution of pregnancy. A total of 758 pregnant women with a positive RT-PCR test for SARS-CoV-2 were enrolled from June 2020 to July 2021. We defined groups using the World Health Organization Severity Classification; cases were pregnant women with severe-critical COVID-19 (n = 123), and controls were subjects with non-severe COVID-19 (n = 635). Data was gathered from clinical files. A multivariate logistic regression analysis was used to adjust odds ratios and their 95% confidence intervals of factors associated with severe-critical COVID-19. Risk factors associated with severe-critical COVID-19 in pregnancy were non-vaccination (OR 10.18), blood type other than O (OR 6.29), maternal age > 35 years (OR 5.76), history of chronic hypertension (OR 5.12), gestational age at infection ≥ 31 weeks (OR 3.28), and multiparity (OR 2.80).
Keywords: COVID-19; SARS-CoV-2; coronavirus infections; pregnancy.