tetano
Editor, Senior Moderator
J Clin Virol
. 2020 May 26;129:104475.
doi: 10.1016/j.jcv.2020.104475. Online ahead of print.
Epidemiological and Clinical Features of 200 Hospitalized Patients With Corona Virus Disease 2019 Outside Wuhan, China: A Descriptive Study
Luhuan Yang[SUP] 1 [/SUP], Jinglan Liu[SUP] 1 [/SUP], Rong Zhang[SUP] 1 [/SUP], Mingwu Li[SUP] 2 [/SUP], Zifeng Li[SUP] 3 [/SUP], Xiaojing Zhou[SUP] 4 [/SUP], Chuanjun Hu[SUP] 5 [/SUP], Fei Tian[SUP] 1 [/SUP], Fating Zhou[SUP] 1 [/SUP], Yunhong Lei[SUP] 6 [/SUP]
Affiliations
Abstract
Background: The recent outbreak of coronavirus disease 2019 (COVID-19) has spread worldwide, with especially severe epidemics occurring in cities across China.
Objectives: To report the epidemiological and clinical futures of the 200 patients infected with COVID-19 in Yichang, Hubei Province, China.
Study design: 200 patients confirmed with COVID-19 in a designated hospital in Yichang from Jan 30 to Feb 8, 2020 were investigated retrospectively. The epidemiological data and clinical characteristics were collected. The data between the ICU patients and non-ICU patients were compared. The patients were followed up till Feb 26, 2020.
Results: Of the 200 hospitalized patients with COVID-19, 98 (49.0 %) were male, and the mean age was 55 years. Eighty-seven (43.5 %) had no linkage to Wuhan or contact history. Familial clustering was found in 34 patients. Sixtyfive (32.5 %) suffered from chronic diseases. The common symptoms included fever (171[85.5 %]), cough (116[58.0 %]), and fatigue (64[32 %]). Most patients had lymphopenia. One hundred and seventy-two (86 %) patients showed typical imaging findings of viral pneumonia. Most patients received antiviral, antibiotic, and corticosteroid treatment. Compared with the non-ICU patients, 29 (14.5 %) patients in the ICU were older and more likely to show dyspnea and complications including ARDS. As of Feb 26, 15 (51.7 %) patients in the ICU had died.
Conclusions: The COVID-19 infection was of clustering onset and can cause severe respiratory disease and even death. The mortality of ICU patients with COVID-19 was considerably high.
Keywords: COVID-19; Clinical features; Epidemiology; Pneumonia; SARS-CoV-2.
. 2020 May 26;129:104475.
doi: 10.1016/j.jcv.2020.104475. Online ahead of print.
Epidemiological and Clinical Features of 200 Hospitalized Patients With Corona Virus Disease 2019 Outside Wuhan, China: A Descriptive Study
Luhuan Yang[SUP] 1 [/SUP], Jinglan Liu[SUP] 1 [/SUP], Rong Zhang[SUP] 1 [/SUP], Mingwu Li[SUP] 2 [/SUP], Zifeng Li[SUP] 3 [/SUP], Xiaojing Zhou[SUP] 4 [/SUP], Chuanjun Hu[SUP] 5 [/SUP], Fei Tian[SUP] 1 [/SUP], Fating Zhou[SUP] 1 [/SUP], Yunhong Lei[SUP] 6 [/SUP]
Affiliations
- PMID: 32485619
- DOI: 10.1016/j.jcv.2020.104475
Abstract
Background: The recent outbreak of coronavirus disease 2019 (COVID-19) has spread worldwide, with especially severe epidemics occurring in cities across China.
Objectives: To report the epidemiological and clinical futures of the 200 patients infected with COVID-19 in Yichang, Hubei Province, China.
Study design: 200 patients confirmed with COVID-19 in a designated hospital in Yichang from Jan 30 to Feb 8, 2020 were investigated retrospectively. The epidemiological data and clinical characteristics were collected. The data between the ICU patients and non-ICU patients were compared. The patients were followed up till Feb 26, 2020.
Results: Of the 200 hospitalized patients with COVID-19, 98 (49.0 %) were male, and the mean age was 55 years. Eighty-seven (43.5 %) had no linkage to Wuhan or contact history. Familial clustering was found in 34 patients. Sixtyfive (32.5 %) suffered from chronic diseases. The common symptoms included fever (171[85.5 %]), cough (116[58.0 %]), and fatigue (64[32 %]). Most patients had lymphopenia. One hundred and seventy-two (86 %) patients showed typical imaging findings of viral pneumonia. Most patients received antiviral, antibiotic, and corticosteroid treatment. Compared with the non-ICU patients, 29 (14.5 %) patients in the ICU were older and more likely to show dyspnea and complications including ARDS. As of Feb 26, 15 (51.7 %) patients in the ICU had died.
Conclusions: The COVID-19 infection was of clustering onset and can cause severe respiratory disease and even death. The mortality of ICU patients with COVID-19 was considerably high.
Keywords: COVID-19; Clinical features; Epidemiology; Pneumonia; SARS-CoV-2.