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J Epidemiol Glob Health . Comparison of the Characteristics of Asymptomatic and Presymptomatic Patients with Coronavirus Disease 2019 in the Republi

tetano

Editor, Senior Moderator
J Epidemiol Glob Health


. 2021 Nov 10.
doi: 10.1007/s44197-021-00011-7. Online ahead of print.
Comparison of the Characteristics of Asymptomatic and Presymptomatic Patients with Coronavirus Disease 2019 in the Republic of Korea


Miri Hyun[SUP] #[/SUP][SUP] 1 [/SUP], Ji Yeon Lee[SUP] #[/SUP][SUP] 1 [/SUP], Jae Seok Park[SUP] 2 [/SUP], Jin Young Kim[SUP] 3 [/SUP], Hyun Ah Kim[SUP] 4 [/SUP]



Affiliations

Abstract

Purpose: This retrospective study aimed to evaluate the baseline characteristics of asymptomatic patients with coronavirus disease 2019 at admission and to follow-up their clinical manifestations and radiological findings during hospitalization.
Methods: Patients with coronavirus disease 2019 who were asymptomatic at admission were divided into two groups-those with no symptoms until discharge (group A) and those who developed symptoms after admission (group B). Patients who could not express their own symptoms were excluded.
Results: Overall, 127 patients were enrolled in the study, of whom 19 and 108 were assigned to groups A and B, respectively. The mean age and median C-reactive protein level were higher in group B than in group A. All patients in group A and one-third of patients in group B had normal initial chest radiographs; 15.8% and 48.1% of patients in groups A and B, respectively, had pneumonia during hospitalization. One patient in group B, whose condition was not severe at the time of admission, deteriorated due to aggravated pneumonia and was transferred to a tertiary hospital.
Conclusion: We summarize the clinical characteristics during hospitalization of patients with coronavirus disease 2019 who were purely asymptomatic at the time of admission. The majority of asymptomatic patients with coronavirus disease 2019 were discharged without significant events during hospitalization. However, it may be difficult to predict subsequent events from initial chest radiographs or oxygen saturation at admission.

Keywords: Asymptomatic; C-reactive protein; Chest radiograph; Coronavirus disease 2019; Pneumonia; Severe acute respiratory syndrome coronavirus 2.
 
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