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J Infect Chemother . A fatal case of extensive gastrointestinal necrosis due to portal and mesenteric vein thrombosis in the post-acute phase of CO

tetano

Editor, Senior Moderator
J Infect Chemother


. 2021 Oct 21;S1341-321X(21)00288-9.
doi: 10.1016/j.jiac.2021.10.015. Online ahead of print.
A fatal case of extensive gastrointestinal necrosis due to portal and mesenteric vein thrombosis in the post-acute phase of COVID-19


Tomohiro Hosoda[SUP] 1 [/SUP], Hideki Orikasa[SUP] 2 [/SUP]



Affiliations

Abstract

Portal vein thrombosis (PVT) is considered a relatively rare thrombotic complication in coronavirus disease 2019 (COVID-19). Most reported cases of PVT develop within 2 weeks from COVID-19 onset. We report a fatal case of extensive gastrointestinal necrosis due to portal and mesenteric vein thrombosis approximately 6 weeks after the onset of critical COVID-19. Excessive elevation of his plasma D-dimer level had continued for weeks during the hospitalization contrary with improvement of respiratory failure. Thrombotic complication should be cautiously paid attention even in the post-acute phase of COVID-19, especially in patients with persistent elevation of plasma D-dimer level.

Keywords: Coronavirus disease 2019; D-dimer; Gastrointestinal necrosis; Portal vein thrombosis; Post-acute phase; SARS-CoV-2.
 
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