tetano
Editor, Senior Moderator
J Infect Chemother
. 2020 Jun 12;S1341-321X(20)30196-3.
doi: 10.1016/j.jiac.2020.06.010. Online ahead of print.
Clinical Characteristics of the Coronavirus Disease 2019 (COVID-19) Outbreak on a Cruise Ship
Yukihiro Yoshimura[SUP] 1 [/SUP], Hiroaki Sasaki[SUP] 2 [/SUP], Hiroshi Horiuchi[SUP] 2 [/SUP], Nobuyuki Miyata[SUP] 2 [/SUP], Natsuo Tachikawa[SUP] 2 [/SUP]
Affiliations
Abstract
Background: A large COVID-19 outbreak occurred on the cruise ship Diamond Princess in February 2020. Little information has been reported about the clinical characteristics of the patients.
Methods: This single-center, retrospective, observational study was conducted in Yokohama, Japan. We included symptomatic patients who were infected on the ship and admitted to our hospital between 5 and 19 February 2020. All the cases were confirmed with SARS-CoV-2 infection by polymerase chain reaction (PCR).
Results: We confirmed 17 cases. The average age was 69 years; 10 patients were Asian and 7 were Caucasian. Eleven patients had one or more chronic diseases. The major symptoms were cough and fever. Chest computed tomography (CT) scans found bilateral ground-glass opacities predominantly in the peripheral area, which were similar to reports from cases in China. C-reactive protein (CRP) levels were higher in severe and critical cases than in mild to moderate cases. The moderate to severe cases reached symptomatic resolution; one of the three critical cases resulted in death due to multiple organ failure. SARS-CoV-2 was detected by PCR at an average of 7 days after symptomatic resolution.
Conclusions: Cough and fever, increased blood CRP levels, and CT findings of bilateral ground-glass opacities predominantly in the peripheral lung were characteristic of the COVID-19 cases in this study. These findings were compatible with those of previous reports.
Keywords: COVID-19; Coronavirus infection; Cruise.
. 2020 Jun 12;S1341-321X(20)30196-3.
doi: 10.1016/j.jiac.2020.06.010. Online ahead of print.
Clinical Characteristics of the Coronavirus Disease 2019 (COVID-19) Outbreak on a Cruise Ship
Yukihiro Yoshimura[SUP] 1 [/SUP], Hiroaki Sasaki[SUP] 2 [/SUP], Hiroshi Horiuchi[SUP] 2 [/SUP], Nobuyuki Miyata[SUP] 2 [/SUP], Natsuo Tachikawa[SUP] 2 [/SUP]
Affiliations
- PMID: 32565152
- DOI: 10.1016/j.jiac.2020.06.010
Abstract
Background: A large COVID-19 outbreak occurred on the cruise ship Diamond Princess in February 2020. Little information has been reported about the clinical characteristics of the patients.
Methods: This single-center, retrospective, observational study was conducted in Yokohama, Japan. We included symptomatic patients who were infected on the ship and admitted to our hospital between 5 and 19 February 2020. All the cases were confirmed with SARS-CoV-2 infection by polymerase chain reaction (PCR).
Results: We confirmed 17 cases. The average age was 69 years; 10 patients were Asian and 7 were Caucasian. Eleven patients had one or more chronic diseases. The major symptoms were cough and fever. Chest computed tomography (CT) scans found bilateral ground-glass opacities predominantly in the peripheral area, which were similar to reports from cases in China. C-reactive protein (CRP) levels were higher in severe and critical cases than in mild to moderate cases. The moderate to severe cases reached symptomatic resolution; one of the three critical cases resulted in death due to multiple organ failure. SARS-CoV-2 was detected by PCR at an average of 7 days after symptomatic resolution.
Conclusions: Cough and fever, increased blood CRP levels, and CT findings of bilateral ground-glass opacities predominantly in the peripheral lung were characteristic of the COVID-19 cases in this study. These findings were compatible with those of previous reports.
Keywords: COVID-19; Coronavirus infection; Cruise.