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J Infect Dev Ctries . Clinical and epidemiological evaluation of influenza and SARS-CoV-2 coinfected cases

tetano

Editor, Senior Moderator
J Infect Dev Ctries


. 2024 Jan 31;18(1):21-26.
doi: 10.3855/jidc.18143. Clinical and epidemiological evaluation of influenza and SARS-CoV-2 coinfected cases

Yeliz Çiçek[SUP] 1 [/SUP], Hıdır Sarı[SUP] 2 [/SUP], Duygu İmre Yetkin[SUP] 3 [/SUP], Mehmet Özel[SUP] 4 [/SUP]



Affiliations
Free article Abstract

Introduction: Coinfection of COVID-19 with influenza pathogens, may complicate the diagnosis, treatment, and prognosis, which is a new concern. This study aims to evaluate COVID-19 and influenza coinfected cases during the flu season, while the SARS-CoV-2 pandemic continues.
Methodology: The study was conducted between November 2021 and January 2022. A total of 1987 (1752 outpatients, 235 inpatients) patients were included, and 44 simultaneous COVID-19 and influenza laboratory-confirmed diagnoses.
Results: During the study period, 1553 patients were diagnosed with COVID-19, 390 influenza, and 44 were diagnosed with coinfection. The incidence of coinfected cases was 2.2% (n = 44) in all patients, When coinfected cases were examined, there was a statistically significant difference between the disease duration in the inpatients (19.86 ± 10.78 days) and the disease duration in the outpatients (7.63 ± 2.25 days) (p < 0.05). 31.8% (n = 14) of coinfected cases were hospitalized, and the mortality rate was 50.0% (n = 7) in hospitalized patients.
Conclusions: Coinfection with SARS-CoV-2 and İnfluenza was not uncommon. Data on coinfected cases are limited in the literature. The coinfection with SARS-CoV-2 and influenza A should be considered in patients with complaints such as fever, myalgia, weakness, shortness of breath, and cough during the flu season. Using the diagnostic test showing two diseases in a single sample may contribute to protecting patient and community health in follow-up and treatment.

Keywords: Coinfection; SARS-CoV-2; flu; influenza.

 
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