tetano
Editor, Senior Moderator
J Infect Dev Ctries
. 2022 Jan 31;16(1):73-80.
doi: 10.3855/jidc.13772.
Evaluation of respiratory anatomical-functional sequelae in patients who recovered from COVID-19
Margarita de la Luz Martinez-Fierro[SUP] 1 [/SUP], Jose Isaias Badillo-Almaraz[SUP] 2 [/SUP], Jose Ramon Muñoz-Torres[SUP] 2 [/SUP], Griselda Aide Cabral Pacheco[SUP] 2 [/SUP], Idalia Garza-Veloz[SUP] 2 [/SUP], Edgar Fernando Gutierrez-Vela[SUP] 3 [/SUP], Lucia Socorro Hernandez-Marquez[SUP] 2 [/SUP], Lizbeth Areli Hernandez-Marquez[SUP] 2 [/SUP], Alondra Daniela Torres-Gaytan[SUP] 2 [/SUP], Juan Carlos Alvarez-Castro[SUP] 2 [/SUP], Claudia Caldera-Villalobos[SUP] 2 [/SUP], Ivan Delgado-Enciso[SUP] 4 [/SUP], Iram Pablo Rodriguez-Sanchez[SUP] 5 [/SUP], Oscar Gustavo Meza-Zavala[SUP] 2 [/SUP], Yolanda Ortiz-Castro[SUP] 2 [/SUP]
Affiliations
Abstract
Introduction: Coronavirus disease 19 (COVID-19) has been a global public health emergency, with 209.89 million cases of infection with SARS-CoV-2 recorded, resulting in 4,401,675 deaths. After recuperation, it is probable that COVID-19 patients have sequelae of the disease. This study aimed to evaluate the respiratory anatomical-functional sequelae in Mexican patients who recovered from COVID-19.
Methodology: This study included twenty-four patients who recovered from COVID-19 and eight non-infected patients (controls). Participants were screened for SARS-CoV-2 and the presence of IgM/IgG antibodies. Pulmonary function and lung anatomical abnormalities were evaluated by spirometry and computerized tomography.
Results: A total of 45.8% of the patients had pulmonary function with obstructive patterns: 70.8% of recovered cases had COVID-19 Reporting and Data System (CO-RADS) 1, 20.8% CO-RADS 3 and 16.7% CO-RADS 4. A total of 35.3% of patients with CO-RADS 1 also showed bilateral nodal growth; 70.8% of patients tested positive for IgG and 8.4% for IgG/IgM, and 20.8% tested negative for both antibodies.
Conclusions: There were respiratory anatomical and functional sequelae in Mexican patients who recovered from COVID-19, with a high occurrence of pulmonary obstructive patterns in the study population. These observations indicate the importance of the routine evaluation of sequelae in Mexican patients who recovered from COVID-19 and the need for strict follow-up to improve the quality of life of these patients.
Keywords: COVID-19; SARS-CoV-2; computerized tomography scan; coronavirus; pulmonary sequelae.
. 2022 Jan 31;16(1):73-80.
doi: 10.3855/jidc.13772.
Evaluation of respiratory anatomical-functional sequelae in patients who recovered from COVID-19
Margarita de la Luz Martinez-Fierro[SUP] 1 [/SUP], Jose Isaias Badillo-Almaraz[SUP] 2 [/SUP], Jose Ramon Muñoz-Torres[SUP] 2 [/SUP], Griselda Aide Cabral Pacheco[SUP] 2 [/SUP], Idalia Garza-Veloz[SUP] 2 [/SUP], Edgar Fernando Gutierrez-Vela[SUP] 3 [/SUP], Lucia Socorro Hernandez-Marquez[SUP] 2 [/SUP], Lizbeth Areli Hernandez-Marquez[SUP] 2 [/SUP], Alondra Daniela Torres-Gaytan[SUP] 2 [/SUP], Juan Carlos Alvarez-Castro[SUP] 2 [/SUP], Claudia Caldera-Villalobos[SUP] 2 [/SUP], Ivan Delgado-Enciso[SUP] 4 [/SUP], Iram Pablo Rodriguez-Sanchez[SUP] 5 [/SUP], Oscar Gustavo Meza-Zavala[SUP] 2 [/SUP], Yolanda Ortiz-Castro[SUP] 2 [/SUP]
Affiliations
- PMID: 35192524
- DOI: 10.3855/jidc.13772
Abstract
Introduction: Coronavirus disease 19 (COVID-19) has been a global public health emergency, with 209.89 million cases of infection with SARS-CoV-2 recorded, resulting in 4,401,675 deaths. After recuperation, it is probable that COVID-19 patients have sequelae of the disease. This study aimed to evaluate the respiratory anatomical-functional sequelae in Mexican patients who recovered from COVID-19.
Methodology: This study included twenty-four patients who recovered from COVID-19 and eight non-infected patients (controls). Participants were screened for SARS-CoV-2 and the presence of IgM/IgG antibodies. Pulmonary function and lung anatomical abnormalities were evaluated by spirometry and computerized tomography.
Results: A total of 45.8% of the patients had pulmonary function with obstructive patterns: 70.8% of recovered cases had COVID-19 Reporting and Data System (CO-RADS) 1, 20.8% CO-RADS 3 and 16.7% CO-RADS 4. A total of 35.3% of patients with CO-RADS 1 also showed bilateral nodal growth; 70.8% of patients tested positive for IgG and 8.4% for IgG/IgM, and 20.8% tested negative for both antibodies.
Conclusions: There were respiratory anatomical and functional sequelae in Mexican patients who recovered from COVID-19, with a high occurrence of pulmonary obstructive patterns in the study population. These observations indicate the importance of the routine evaluation of sequelae in Mexican patients who recovered from COVID-19 and the need for strict follow-up to improve the quality of life of these patients.
Keywords: COVID-19; SARS-CoV-2; computerized tomography scan; coronavirus; pulmonary sequelae.