tetano
Editor, Senior Moderator
J Infect Dev Ctries
. 2023 Feb 28;17(2):241-250.
doi: 10.3855/jidc.16801.
Severe acute respiratory syndrome by influenza and factors associated with death in older adults: a population study
Thayna Martins Gonçalves[SUP] 1 [/SUP], Patrícia Mitsue Saruhashi Shimabukuro[SUP] 2 [/SUP], Karen Renata Nakamura Hiraki[SUP] 3 [/SUP], Paulo Henrique Braz-Silva[SUP] 4 [/SUP], Simone Giannecchini[SUP] 5 [/SUP], Kelvin Kai-Wang To[SUP] 6 [/SUP], Monica Taminato[SUP] 2 [/SUP], Richarlisson Borges de Morais[SUP] 2 [/SUP]
Affiliations
Abstract
Introduction: Influenza is characterized by an acute viral infection, which can lead to severe conditions and death, especially in vulnerable populations, such as older adults. Therefore, we sought to analyze cases of severe acute respiratory syndrome (SARS) due to influenza in older adults registered in Brazil and investigate the factors related to death due to this disease.
Methodology: This is a cross-sectional, population-based study that used secondary data from the Influenza Epidemiological Surveillance Information System (IESIS-Influenza). Older adults aged 60 years and above with laboratory diagnosis of influenza were included.
Results: A total of 3,547 older adults with SARS due to influenza were included, out of which 1,185 cases with death as the outcome were identified. Among older adults with death as the outcome, 87.4% were not vaccinated against influenza. The main risk factors for death were invasive ventilatory support use, intensive care unit admission, brown skin color and dyspnea (p < 0.001).
Conclusions: This study described the profile of older adults with SARS due to influenza in Brazil. Factors associated with death in this population were identified. Moreover, the need to encourage compliance with vaccination among older adults is evident in order to prevent severe cases and unfavorable outcomes related to influenza.
Keywords: Influenza; death; elderly; infection; risk factors; vaccine.
. 2023 Feb 28;17(2):241-250.
doi: 10.3855/jidc.16801.
Severe acute respiratory syndrome by influenza and factors associated with death in older adults: a population study
Thayna Martins Gonçalves[SUP] 1 [/SUP], Patrícia Mitsue Saruhashi Shimabukuro[SUP] 2 [/SUP], Karen Renata Nakamura Hiraki[SUP] 3 [/SUP], Paulo Henrique Braz-Silva[SUP] 4 [/SUP], Simone Giannecchini[SUP] 5 [/SUP], Kelvin Kai-Wang To[SUP] 6 [/SUP], Monica Taminato[SUP] 2 [/SUP], Richarlisson Borges de Morais[SUP] 2 [/SUP]
Affiliations
- PMID: 36897907
- DOI: 10.3855/jidc.16801
Abstract
Introduction: Influenza is characterized by an acute viral infection, which can lead to severe conditions and death, especially in vulnerable populations, such as older adults. Therefore, we sought to analyze cases of severe acute respiratory syndrome (SARS) due to influenza in older adults registered in Brazil and investigate the factors related to death due to this disease.
Methodology: This is a cross-sectional, population-based study that used secondary data from the Influenza Epidemiological Surveillance Information System (IESIS-Influenza). Older adults aged 60 years and above with laboratory diagnosis of influenza were included.
Results: A total of 3,547 older adults with SARS due to influenza were included, out of which 1,185 cases with death as the outcome were identified. Among older adults with death as the outcome, 87.4% were not vaccinated against influenza. The main risk factors for death were invasive ventilatory support use, intensive care unit admission, brown skin color and dyspnea (p < 0.001).
Conclusions: This study described the profile of older adults with SARS due to influenza in Brazil. Factors associated with death in this population were identified. Moreover, the need to encourage compliance with vaccination among older adults is evident in order to prevent severe cases and unfavorable outcomes related to influenza.
Keywords: Influenza; death; elderly; infection; risk factors; vaccine.