tetano
Editor, Senior Moderator
J Infect Dis
. 2021 Nov 20;jiab551.
doi: 10.1093/infdis/jiab551. Online ahead of print.
Rapid SARS-CoV-2 Inactivation in a Simulated Hospital Room Using a Mobile and Autonomous Robot Emitting Ultraviolet-C Light
Cristina Lorca-Oró[SUP] 1 [/SUP], Jordi Vila[SUP] 2 3 [/SUP], Patricia Pleguezuelos[SUP] 1 [/SUP], Júlia Vergara-Alert[SUP] 1 [/SUP], Jordi Rodon[SUP] 1 [/SUP], Natàlia Majó[SUP] 1 4 [/SUP], Sergio López[SUP] 1 [/SUP], Joaquim Segalés[SUP] 1 4 [/SUP], Francesc Saldaña-Buesa[SUP] 5 [/SUP], Maria Visa-Boladeras[SUP] 6 [/SUP], Andreu Veà-Baró[SUP] 2 5 [/SUP], Josep Maria Campistol[SUP] 2 3 [/SUP], Xavier Abad[SUP] 1 [/SUP]
Affiliations
Abstract
The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) since 2019 has made mask-wearing, physical distancing, hygiene, and disinfection complementary measures to control virus transmission. Especially for health facilities, we evaluated the efficacy of an UV-C autonomous robot to inactivate SARS-CoV-2 desiccated on potentially contaminated surfaces. ASSUM (autonomous sanitary sterilization ultraviolet machine) robot was used in an experimental box simulating a hospital intensive care unit room. Desiccated SARS-CoV-2 samples were exposed to UV-C in 2 independent runs of 5, 12, and 20 minutes. Residual virus was eluted from surfaces and viral titration was carried out in Vero E6 cells. ASSUM inactivated SARS-CoV-2 by ≥ 99.91% to ≥ 99.99% titer reduction with 12 minutes or longer of UV-C exposure and onwards and a minimum distance of 100cm between the device and the SARS-CoV-2 desiccated samples. This study demonstrates that ASSUM UV-C device is able to inactivate SARS-CoV-2 within a few minutes.
Keywords: SARS-CoV-2 inactivation; UV-C radiation; autonomous robots; exponential viral-load reduction; virus inactivation.
. 2021 Nov 20;jiab551.
doi: 10.1093/infdis/jiab551. Online ahead of print.
Rapid SARS-CoV-2 Inactivation in a Simulated Hospital Room Using a Mobile and Autonomous Robot Emitting Ultraviolet-C Light
Cristina Lorca-Oró[SUP] 1 [/SUP], Jordi Vila[SUP] 2 3 [/SUP], Patricia Pleguezuelos[SUP] 1 [/SUP], Júlia Vergara-Alert[SUP] 1 [/SUP], Jordi Rodon[SUP] 1 [/SUP], Natàlia Majó[SUP] 1 4 [/SUP], Sergio López[SUP] 1 [/SUP], Joaquim Segalés[SUP] 1 4 [/SUP], Francesc Saldaña-Buesa[SUP] 5 [/SUP], Maria Visa-Boladeras[SUP] 6 [/SUP], Andreu Veà-Baró[SUP] 2 5 [/SUP], Josep Maria Campistol[SUP] 2 3 [/SUP], Xavier Abad[SUP] 1 [/SUP]
Affiliations
- PMID: 34904659
- DOI: 10.1093/infdis/jiab551
Abstract
The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) since 2019 has made mask-wearing, physical distancing, hygiene, and disinfection complementary measures to control virus transmission. Especially for health facilities, we evaluated the efficacy of an UV-C autonomous robot to inactivate SARS-CoV-2 desiccated on potentially contaminated surfaces. ASSUM (autonomous sanitary sterilization ultraviolet machine) robot was used in an experimental box simulating a hospital intensive care unit room. Desiccated SARS-CoV-2 samples were exposed to UV-C in 2 independent runs of 5, 12, and 20 minutes. Residual virus was eluted from surfaces and viral titration was carried out in Vero E6 cells. ASSUM inactivated SARS-CoV-2 by ≥ 99.91% to ≥ 99.99% titer reduction with 12 minutes or longer of UV-C exposure and onwards and a minimum distance of 100cm between the device and the SARS-CoV-2 desiccated samples. This study demonstrates that ASSUM UV-C device is able to inactivate SARS-CoV-2 within a few minutes.
Keywords: SARS-CoV-2 inactivation; UV-C radiation; autonomous robots; exponential viral-load reduction; virus inactivation.
