tetano
Editor, Senior Moderator
J Infect Dis
. 2024 Apr 6:jiae179.
doi: 10.1093/infdis/jiae179. Online ahead of print. What is the economic benefit of annual COVID-19 vaccination from the adult individual perspective?
Sarah M Bartsch[SUP] 1 2 3 [/SUP], Kelly J O'Shea[SUP] 1 2 3 [/SUP], Colleen Weatherwax[SUP] 1 2 3 [/SUP], Ulrich Strych[SUP] 4 [/SUP], Kavya Velmurugan[SUP] 1 2 3 [/SUP], Danielle C John[SUP] 1 2 3 [/SUP], Maria Elena Bottazzi[SUP] 4 5 [/SUP], Mustafa Hussein[SUP] 6 [/SUP], Marie F Martinez[SUP] 1 2 3 [/SUP], Kevin L Chin[SUP] 1 2 3 [/SUP], Allan Ciciriello[SUP] 4 [/SUP], Jessie Heneghan[SUP] 1 2 3 [/SUP], Alexis Dibbs[SUP] 1 2 3 [/SUP], Sheryl A Scannell[SUP] 1 2 3 [/SUP], Peter J Hotez[SUP] 4 5 [/SUP], Bruce Y Lee[SUP] 1 2 3 [/SUP]
Affiliations
Background: With COVID-19 vaccination no longer mandated by many businesses/organizations, it is now up to individuals to decide whether to get any new boosters/updated vaccines going forward.
Methods: We developed a Markov model representing the potential clinical/economic outcomes from an individual perspective in the United States of getting versus not getting an annual COVID-19 vaccine.
Results: For an 18-49-year-old, getting vaccinated at its current price ($60) can save the individual on average $30-$603 if the individual is uninsured and $4-$437 if the individual has private insurance, as long as the starting vaccine efficacy against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is ≥50% and the weekly risk of getting infected is ≥0.2%, corresponding to an individual interacting with 9 other people in a day under Winter 2023-2024 Omicron SARS-CoV-2 variant conditions with an average infection prevalence of 10%. For a 50-64-year-old, these cost-savings increase to $111-$1,278 and $119-$1,706, for someone without and with insurance, respectively. The risk threshold increases to ≥0.4% (interacting with 19 people/day), when the individual has 13.4% pre-existing protection against infection (e.g., vaccinated 9 months earlier).
Conclusion: There is both clinical and economic incentive for the individual to continue to get vaccinated against COVID-19 each year.
Keywords: Booster; COVID-19; Economic; Individual; Model; Vaccination.
. 2024 Apr 6:jiae179.
doi: 10.1093/infdis/jiae179. Online ahead of print. What is the economic benefit of annual COVID-19 vaccination from the adult individual perspective?
Sarah M Bartsch[SUP] 1 2 3 [/SUP], Kelly J O'Shea[SUP] 1 2 3 [/SUP], Colleen Weatherwax[SUP] 1 2 3 [/SUP], Ulrich Strych[SUP] 4 [/SUP], Kavya Velmurugan[SUP] 1 2 3 [/SUP], Danielle C John[SUP] 1 2 3 [/SUP], Maria Elena Bottazzi[SUP] 4 5 [/SUP], Mustafa Hussein[SUP] 6 [/SUP], Marie F Martinez[SUP] 1 2 3 [/SUP], Kevin L Chin[SUP] 1 2 3 [/SUP], Allan Ciciriello[SUP] 4 [/SUP], Jessie Heneghan[SUP] 1 2 3 [/SUP], Alexis Dibbs[SUP] 1 2 3 [/SUP], Sheryl A Scannell[SUP] 1 2 3 [/SUP], Peter J Hotez[SUP] 4 5 [/SUP], Bruce Y Lee[SUP] 1 2 3 [/SUP]
Affiliations
- PMID: 38581432
- DOI: 10.1093/infdis/jiae179
Background: With COVID-19 vaccination no longer mandated by many businesses/organizations, it is now up to individuals to decide whether to get any new boosters/updated vaccines going forward.
Methods: We developed a Markov model representing the potential clinical/economic outcomes from an individual perspective in the United States of getting versus not getting an annual COVID-19 vaccine.
Results: For an 18-49-year-old, getting vaccinated at its current price ($60) can save the individual on average $30-$603 if the individual is uninsured and $4-$437 if the individual has private insurance, as long as the starting vaccine efficacy against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is ≥50% and the weekly risk of getting infected is ≥0.2%, corresponding to an individual interacting with 9 other people in a day under Winter 2023-2024 Omicron SARS-CoV-2 variant conditions with an average infection prevalence of 10%. For a 50-64-year-old, these cost-savings increase to $111-$1,278 and $119-$1,706, for someone without and with insurance, respectively. The risk threshold increases to ≥0.4% (interacting with 19 people/day), when the individual has 13.4% pre-existing protection against infection (e.g., vaccinated 9 months earlier).
Conclusion: There is both clinical and economic incentive for the individual to continue to get vaccinated against COVID-19 each year.
Keywords: Booster; COVID-19; Economic; Individual; Model; Vaccination.