tetano
Editor, Senior Moderator
J Infect Public Health
. 2021 Jul 18;14(9):1127-1132.
doi: 10.1016/j.jiph.2021.07.011. Online ahead of print.
A familial cluster of COVID-19 infection in a northern Chinese region
Cai-Xia Liu[SUP] 1 [/SUP], Zhi-Hui Liu[SUP] 2 [/SUP], Lu-Yao Sun[SUP] 1 [/SUP], Kai-Yu Zhang[SUP] 3 [/SUP], Yi-Zhe Sun[SUP] 4 [/SUP]
Affiliations
Abstract
Objective: Currently, coronavirus disease 2019 (COVID-19) has spread worldwide and become a global health concern. Here, we report a familial cluster of six patients infected with severe acute respiratory coronavirus 2 (SARS-CoV-2) in a northern Chinese region and share our local experience with regard the control of COVID-19.
Methods: The demographic data, clinical features, laboratory examinations, and epidemiological characteristics of enrolled cases were collected and analyzed. Two family members (Cases 1 and 2) had Hubei exposure history and were admitted to the hospital with a confirmed diagnosis of COVID-19; eight familial members who had contact with them during the incubation period underwent quarantine in a hospital. We closely followed up all the family members and analyzed their clinical outcome.
Results: Case 3 had negative SARS-CoV-2 reverse transcription-polymerase chain reaction (RT-PCR) results but was suspected to have COVID-19 because of radiographic abnormalities. Cases 4 and 5 developed symptomatic COVID-19. Case 6 was considered an asymptomatic carrier as his SARS-CoV-2 RT-PCR result was positive. The other four family members with close contacts to COVID-19 patients had no evidence of SARS-CoV-2 infection.
Conclusions: Our findings suggest that COVID-19 has infectivity during the incubation period and preventive quarantine is effective for controlling an outbreak of COVID-19 infection.
Keywords: Coronavirus disease 2019; Family cluster; Incubation period; Quarantine.
. 2021 Jul 18;14(9):1127-1132.
doi: 10.1016/j.jiph.2021.07.011. Online ahead of print.
A familial cluster of COVID-19 infection in a northern Chinese region
Cai-Xia Liu[SUP] 1 [/SUP], Zhi-Hui Liu[SUP] 2 [/SUP], Lu-Yao Sun[SUP] 1 [/SUP], Kai-Yu Zhang[SUP] 3 [/SUP], Yi-Zhe Sun[SUP] 4 [/SUP]
Affiliations
- PMID: 34343962
- DOI: 10.1016/j.jiph.2021.07.011
Abstract
Objective: Currently, coronavirus disease 2019 (COVID-19) has spread worldwide and become a global health concern. Here, we report a familial cluster of six patients infected with severe acute respiratory coronavirus 2 (SARS-CoV-2) in a northern Chinese region and share our local experience with regard the control of COVID-19.
Methods: The demographic data, clinical features, laboratory examinations, and epidemiological characteristics of enrolled cases were collected and analyzed. Two family members (Cases 1 and 2) had Hubei exposure history and were admitted to the hospital with a confirmed diagnosis of COVID-19; eight familial members who had contact with them during the incubation period underwent quarantine in a hospital. We closely followed up all the family members and analyzed their clinical outcome.
Results: Case 3 had negative SARS-CoV-2 reverse transcription-polymerase chain reaction (RT-PCR) results but was suspected to have COVID-19 because of radiographic abnormalities. Cases 4 and 5 developed symptomatic COVID-19. Case 6 was considered an asymptomatic carrier as his SARS-CoV-2 RT-PCR result was positive. The other four family members with close contacts to COVID-19 patients had no evidence of SARS-CoV-2 infection.
Conclusions: Our findings suggest that COVID-19 has infectivity during the incubation period and preventive quarantine is effective for controlling an outbreak of COVID-19 infection.
Keywords: Coronavirus disease 2019; Family cluster; Incubation period; Quarantine.