tetano
Editor, Senior Moderator
J Infect Public Health
. 2022 Jan 31;15(3):312-314.
doi: 10.1016/j.jiph.2022.01.014. Online ahead of print.
Risk factors associated with asymptomatic hypoxemia among COVID-19 patients: a retrospective study using the nationwide Japanese registry, COVIREGI-JP
Yutaro Akiyama[SUP] 1 [/SUP], Shinichiro Morioka[SUP] 2 [/SUP], Yusuke Asai[SUP] 3 [/SUP], Lubna Sato[SUP] 1 [/SUP], Setsuko Suzuki[SUP] 1 [/SUP], Sho Saito[SUP] 4 [/SUP], Nobuaki Matsunaga[SUP] 3 [/SUP], Kayoko Hayakawa[SUP] 5 [/SUP], Norio Ohmagari[SUP] 5 [/SUP]
Affiliations
Abstract
Deaths of home-care patients with coronavirus disease (COVID-19) have become a social problem. One of their causes is hypoxemia without dyspnea which delays seeking medical attention. This was a retrospective study including patients registered in the COVID-19 Registry Japan, in which hospitalized patients with COVID-19 in 227 participating healthcare facilities were enrolled. The enrolled patients were divided into two groups: non-dyspneic patients with a peripheral capillary oxygen saturation (SpO[SUB]2[/SUB]) ≤ 93% on admission (the hypoxemia without dyspnea group) and non-dyspneic patients with an SpO[SUB]2[/SUB]> 93% (the control group). We conducted a multivariate logistic regression analysis to identify the factors associated with hypoxemia without dyspnea. 21544 patients were enrolled, 1035 (4.8%) patients were in the hypoxemia without dyspnea group, and 20509 (95.2%) patients were in the control group. The median respiratory rate (RR) of the hypoxemia without dyspnea group was higher than that of the control group (31/min vs. 18/min, p < 0.001). Age> 65, male, body mass index> 25, smoking, chronic obstructive pulmonary disease, other chronic lung disease, and diabetes mellitus were the independent factors associated with hypoxemia without dyspnea. Patients with those background should be closely monitored. RR is an important indicator of hypoxemia, even in the absence of dyspnea.
Keywords: COVID-19; Registry; Respiratory rate; Risk factors; Silent hypoxia.
. 2022 Jan 31;15(3):312-314.
doi: 10.1016/j.jiph.2022.01.014. Online ahead of print.
Risk factors associated with asymptomatic hypoxemia among COVID-19 patients: a retrospective study using the nationwide Japanese registry, COVIREGI-JP
Yutaro Akiyama[SUP] 1 [/SUP], Shinichiro Morioka[SUP] 2 [/SUP], Yusuke Asai[SUP] 3 [/SUP], Lubna Sato[SUP] 1 [/SUP], Setsuko Suzuki[SUP] 1 [/SUP], Sho Saito[SUP] 4 [/SUP], Nobuaki Matsunaga[SUP] 3 [/SUP], Kayoko Hayakawa[SUP] 5 [/SUP], Norio Ohmagari[SUP] 5 [/SUP]
Affiliations
- PMID: 35124327
- DOI: 10.1016/j.jiph.2022.01.014
Abstract
Deaths of home-care patients with coronavirus disease (COVID-19) have become a social problem. One of their causes is hypoxemia without dyspnea which delays seeking medical attention. This was a retrospective study including patients registered in the COVID-19 Registry Japan, in which hospitalized patients with COVID-19 in 227 participating healthcare facilities were enrolled. The enrolled patients were divided into two groups: non-dyspneic patients with a peripheral capillary oxygen saturation (SpO[SUB]2[/SUB]) ≤ 93% on admission (the hypoxemia without dyspnea group) and non-dyspneic patients with an SpO[SUB]2[/SUB]> 93% (the control group). We conducted a multivariate logistic regression analysis to identify the factors associated with hypoxemia without dyspnea. 21544 patients were enrolled, 1035 (4.8%) patients were in the hypoxemia without dyspnea group, and 20509 (95.2%) patients were in the control group. The median respiratory rate (RR) of the hypoxemia without dyspnea group was higher than that of the control group (31/min vs. 18/min, p < 0.001). Age> 65, male, body mass index> 25, smoking, chronic obstructive pulmonary disease, other chronic lung disease, and diabetes mellitus were the independent factors associated with hypoxemia without dyspnea. Patients with those background should be closely monitored. RR is an important indicator of hypoxemia, even in the absence of dyspnea.
Keywords: COVID-19; Registry; Respiratory rate; Risk factors; Silent hypoxia.