tetano
Editor, Senior Moderator
J Int Assoc Provid AIDS Care
. Jan-Dec 2022;21:23259582221077943.
doi: 10.1177/23259582221077943.
Seroprevalence of Anti-SARS-CoV-2 IgG Antibodies among HIV Infected Individuals Attending ART Centre at Pune: A Cross-Sectional Study
Manisha Ghate[SUP] 1 [/SUP], Pallavi Shidhaye[SUP] 1 [/SUP], Shraddha Gurav[SUP] 1 [/SUP], Keshav Gadhe[SUP] 1 [/SUP], Varsha Kale[SUP] 1 [/SUP], Preeti Jain[SUP] 1 [/SUP], Madhuri Thakar[SUP] 1 [/SUP]
Affiliations
Abstract
Background: We aimed to determine the anti-SARS-CoV-2 IgG antibodies among people living with HIV (PLHIV) in Pune, India. Methods: This cross-sectional study was conducted between March 2021 and June 2021. Demographic and clinical information related to coronavirus disease 2019 (COVID-19) were recorded on structured questionnaires. Blood samples were collected and tested for anti-SARS-CoV-2 IgG antibodies using commercial ELISA. Results: Of the 405 HIV infected individuals enrolled in the study, 223(55.1%) were females. Mean age and CD4 count of participants were 42 years (SD: 10) and 626 cells/mm[SUP]3[/SUP] (SD: 284) respectively. A total of 382 (95%) PLHIV were virologically suppressed. The seropositivity against SARS-CoV-2 was found in 221 PLHIV (54.6%, 95% CI: 49.7-59.4). No significant association was found between demographic or clinical factors and seropositivity. Conclusion: A high prevalence of anti-SARS-CoV-2 IgG antibodies was found among PLHIV attending ART centre indicating an exposure to the virus among them.
Keywords: COVID-19; HIV; SARS-CoV-2; antibodies; seroprevalence.
. Jan-Dec 2022;21:23259582221077943.
doi: 10.1177/23259582221077943.
Seroprevalence of Anti-SARS-CoV-2 IgG Antibodies among HIV Infected Individuals Attending ART Centre at Pune: A Cross-Sectional Study
Manisha Ghate[SUP] 1 [/SUP], Pallavi Shidhaye[SUP] 1 [/SUP], Shraddha Gurav[SUP] 1 [/SUP], Keshav Gadhe[SUP] 1 [/SUP], Varsha Kale[SUP] 1 [/SUP], Preeti Jain[SUP] 1 [/SUP], Madhuri Thakar[SUP] 1 [/SUP]
Affiliations
- PMID: 35128977
- DOI: 10.1177/23259582221077943
Abstract
Background: We aimed to determine the anti-SARS-CoV-2 IgG antibodies among people living with HIV (PLHIV) in Pune, India. Methods: This cross-sectional study was conducted between March 2021 and June 2021. Demographic and clinical information related to coronavirus disease 2019 (COVID-19) were recorded on structured questionnaires. Blood samples were collected and tested for anti-SARS-CoV-2 IgG antibodies using commercial ELISA. Results: Of the 405 HIV infected individuals enrolled in the study, 223(55.1%) were females. Mean age and CD4 count of participants were 42 years (SD: 10) and 626 cells/mm[SUP]3[/SUP] (SD: 284) respectively. A total of 382 (95%) PLHIV were virologically suppressed. The seropositivity against SARS-CoV-2 was found in 221 PLHIV (54.6%, 95% CI: 49.7-59.4). No significant association was found between demographic or clinical factors and seropositivity. Conclusion: A high prevalence of anti-SARS-CoV-2 IgG antibodies was found among PLHIV attending ART centre indicating an exposure to the virus among them.
Keywords: COVID-19; HIV; SARS-CoV-2; antibodies; seroprevalence.