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J Int Med Res . Quality of life and persistence of COVID-19 symptoms 90 days after hospital discharge

tetano

Editor, Senior Moderator
J Int Med Res


. 2022 Jul;50(7):3000605221110492.
doi: 10.1177/03000605221110492.
Quality of life and persistence of COVID-19 symptoms 90 days after hospital discharge


Carolina Muñoz-Corona[SUP] 1 [/SUP], Lizeth Guadalupe Gutiérrez-Canales[SUP] 2 [/SUP], Claudia Ortiz-Ledesma[SUP] 3 [/SUP], Liz Jovanna Martínez-Navarro[SUP] 3 [/SUP], Alejandro E Macías[SUP] 4 [/SUP], David Alejandro Scavo-Montes[SUP] 5 [/SUP], Eduardo Guaní-Guerra[SUP] 2 6 [/SUP]



Affiliations

Abstract

Objective: We aimed to describe the persistence of symptoms in coronavirus disease 2019 (COVID-19) and quality of life (QoL) among patients 90 days after their discharge from the hospital for infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and to determine differences in QoL domains concerning the absence or presence of persistent symptoms.
Methods: To measure QoL, we used a validated Spanish version of the 36-item Short Form Health Survey (SF-36).
Results: We included 141 patients. Ninety days after discharge, COVID-19 symptoms persisted in 107 patients (75.9%), with fatigue (55.3%) and joint pain (46.8%) being the most frequent. According to the SF-36, the role-physical score was the dimension with the lowest values (median score, 25; interquartile range, 0-75). Patients with joint pain, fatigue, and dyspnea had lower scores than patients without those symptoms, with 10 of the 13 evaluated SF-36 scales showing lower levels.
Conclusion: Ninety days after hospital discharge from COVID-19 reference centers, most patients had persistent symptoms and had lower SF-36 scores than patients without symptoms. It is important to follow-up patients discharged from the hospital after SARS-CoV-2 infection, ideally through a post-COVID-19 health care clinic and rehabilitation program, to improve QoL in these patients.

Keywords: 36-item Short Form Health Survey; Quality of life; coronavirus disease 2019; long COVID; persistent COVID-19 symptoms; severe acute respiratory syndrome coronavirus 2.
 
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