tetano
Editor, Senior Moderator
J Med Case Rep
. 2021 Dec 13;15(1):606.
doi: 10.1186/s13256-021-03205-6.
A full-term pregnant woman with secondary Evans syndrome caused by severe coronavirus disease 2019: a case report
Damai Santosa[SUP] 1 [/SUP], Muchlis A U Sofro[SUP] 2 [/SUP], Farida[SUP] 3 [/SUP], Nurvita Nindita[SUP] 4 [/SUP], Eko A Pangarsa[SUP] 1 [/SUP], Budi Setiawan[SUP] 1 [/SUP], Daniel Rizky[SUP] 5 [/SUP], Catharina Suharti[SUP] 1 6 [/SUP]
Affiliations
Abstract
Background: In this report, we describe a very challenging case of a patient with secondary Evans syndrome caused by severe coronavirus disease 2019 infection in a pregnant full-term woman.
Case presentation: A 29-year-old full-term pregnant Indonesian woman presented with gross hematuria, dry cough, fever, dyspnea, nausea, anosmia, and fatigue 5 days after confirmation of coronavirus disease 2019 infection. Laboratory examinations showed very severe thrombocytopenia, increased indirect bilirubin, and a positive direct Coombs' test. From peripheral blood, there was an increased number of spherocytes, which indicated an autoimmune hemolytic process. Antinuclear antibody and anti-double-stranded DNA test results were negative, and her virology serological markers are also negative for human immunodeficiency virus, cytomegalovirus, and hepatitis B and C. Despite aggressive treatment with platelet transfusion, high-dose steroid, and thrombopoietin receptor agonists, the platelet count did not recover, and a speculative cesarean delivery had to be done with a very low platelet count.
Keywords: C-section delivery; COVID-19; Evans syndrome.
. 2021 Dec 13;15(1):606.
doi: 10.1186/s13256-021-03205-6.
A full-term pregnant woman with secondary Evans syndrome caused by severe coronavirus disease 2019: a case report
Damai Santosa[SUP] 1 [/SUP], Muchlis A U Sofro[SUP] 2 [/SUP], Farida[SUP] 3 [/SUP], Nurvita Nindita[SUP] 4 [/SUP], Eko A Pangarsa[SUP] 1 [/SUP], Budi Setiawan[SUP] 1 [/SUP], Daniel Rizky[SUP] 5 [/SUP], Catharina Suharti[SUP] 1 6 [/SUP]
Affiliations
- PMID: 34903274
- DOI: 10.1186/s13256-021-03205-6
Abstract
Background: In this report, we describe a very challenging case of a patient with secondary Evans syndrome caused by severe coronavirus disease 2019 infection in a pregnant full-term woman.
Case presentation: A 29-year-old full-term pregnant Indonesian woman presented with gross hematuria, dry cough, fever, dyspnea, nausea, anosmia, and fatigue 5 days after confirmation of coronavirus disease 2019 infection. Laboratory examinations showed very severe thrombocytopenia, increased indirect bilirubin, and a positive direct Coombs' test. From peripheral blood, there was an increased number of spherocytes, which indicated an autoimmune hemolytic process. Antinuclear antibody and anti-double-stranded DNA test results were negative, and her virology serological markers are also negative for human immunodeficiency virus, cytomegalovirus, and hepatitis B and C. Despite aggressive treatment with platelet transfusion, high-dose steroid, and thrombopoietin receptor agonists, the platelet count did not recover, and a speculative cesarean delivery had to be done with a very low platelet count.
Keywords: C-section delivery; COVID-19; Evans syndrome.