tetano
Editor, Senior Moderator
J Med Virol
. 2021 May 27.
doi: 10.1002/jmv.27104. Online ahead of print.
Factors Associated with Hospital Readmissions among Patients with COVID-19: A Single Center Experience
Geneva Guarin[SUP] 1 [/SUP], Kevin Bryan Lo[SUP] 1 [/SUP], Ruchika Bhargav[SUP] 1 [/SUP], Grace Salacup[SUP] 1 [/SUP], Ammaar Wattoo[SUP] 1 [/SUP], Jean-Gabriel Coignet[SUP] 2 [/SUP], Robert DeJoy[SUP] 1 [/SUP], Zurab Azmaiparashvili[SUP] 1 3 [/SUP], Gabriel Patarroyo-Aponte[SUP] 3 4 [/SUP], Glenn Eiger[SUP] 1 3 4 [/SUP], Janani Rangaswami[SUP] 1 3 [/SUP]
Affiliations
Abstract
Objectives: Identify factors associated with readmission after an index hospital admission for Coronavirus Disease 2019 (COVID-19) infection in a single center serving an underserved and predominantly minority population.
Methods: This retrospective descriptive study included 275 patients who tested COVID-19 positive via reverse transcriptase-polymerase chain reaction assay at our institution and who survived the index hospitalization.
Outcomes: Main outcomes were 1-month and 6-month readmission rates after an index hospitalization for COVID-19. Mortality rate among the readmitted patients was also determined. Factors independently associated with readmission were investigated using multivariable logistic regression.
Results: A final sample of 275 patients were included. The mean age was 64.69 ±14.64 (SD) 133 (48%) were female and 194 (70%) were African American. Their chronic medical conditions included hypertension 203 (74%) and diabetes mellitus 121 (44%). After the hospitalization, 1-month readmission rate was 7.6%, while 6-month readmission rate was 24%. 9% of patients who were readmitted subsequently died. Coronary artery disease (CAD) was significantly associated with 6-month readmission OR 2.15 (95% CI 1.04-4.44; p=0.039) after adjustment for age, gender, ethnicity and comorbidities. Readmissions were due to cardiac, respiratory, and musculoskeletal symptoms. Hispanic ethnicity was associated with increased readmission OR 3.16 (95% CI 1.01-9.88; p=0.048). No significant difference was found between inflammatory markers or clinical outcomes during the index hospitalization among patients who were readmitted compared to those who were not.
Conclusions: A significant number of patients hospitalized for COVID-19 may be readmitted. Presence of CAD is independently associated with high rates of 6-month readmission. This article is protected by copyright. All rights reserved.
Keywords: COVID-19; mortality; novel coronavirus; readmission.
. 2021 May 27.
doi: 10.1002/jmv.27104. Online ahead of print.
Factors Associated with Hospital Readmissions among Patients with COVID-19: A Single Center Experience
Geneva Guarin[SUP] 1 [/SUP], Kevin Bryan Lo[SUP] 1 [/SUP], Ruchika Bhargav[SUP] 1 [/SUP], Grace Salacup[SUP] 1 [/SUP], Ammaar Wattoo[SUP] 1 [/SUP], Jean-Gabriel Coignet[SUP] 2 [/SUP], Robert DeJoy[SUP] 1 [/SUP], Zurab Azmaiparashvili[SUP] 1 3 [/SUP], Gabriel Patarroyo-Aponte[SUP] 3 4 [/SUP], Glenn Eiger[SUP] 1 3 4 [/SUP], Janani Rangaswami[SUP] 1 3 [/SUP]
Affiliations
- PMID: 34042189
- DOI: 10.1002/jmv.27104
Abstract
Objectives: Identify factors associated with readmission after an index hospital admission for Coronavirus Disease 2019 (COVID-19) infection in a single center serving an underserved and predominantly minority population.
Methods: This retrospective descriptive study included 275 patients who tested COVID-19 positive via reverse transcriptase-polymerase chain reaction assay at our institution and who survived the index hospitalization.
Outcomes: Main outcomes were 1-month and 6-month readmission rates after an index hospitalization for COVID-19. Mortality rate among the readmitted patients was also determined. Factors independently associated with readmission were investigated using multivariable logistic regression.
Results: A final sample of 275 patients were included. The mean age was 64.69 ±14.64 (SD) 133 (48%) were female and 194 (70%) were African American. Their chronic medical conditions included hypertension 203 (74%) and diabetes mellitus 121 (44%). After the hospitalization, 1-month readmission rate was 7.6%, while 6-month readmission rate was 24%. 9% of patients who were readmitted subsequently died. Coronary artery disease (CAD) was significantly associated with 6-month readmission OR 2.15 (95% CI 1.04-4.44; p=0.039) after adjustment for age, gender, ethnicity and comorbidities. Readmissions were due to cardiac, respiratory, and musculoskeletal symptoms. Hispanic ethnicity was associated with increased readmission OR 3.16 (95% CI 1.01-9.88; p=0.048). No significant difference was found between inflammatory markers or clinical outcomes during the index hospitalization among patients who were readmitted compared to those who were not.
Conclusions: A significant number of patients hospitalized for COVID-19 may be readmitted. Presence of CAD is independently associated with high rates of 6-month readmission. This article is protected by copyright. All rights reserved.
Keywords: COVID-19; mortality; novel coronavirus; readmission.