tetano
Editor, Senior Moderator
J Med Virol
. 2021 Apr 8.
doi: 10.1002/jmv.27002. Online ahead of print.
Hypoalbuminemia in Patients Following Their Recovery from Severe Coronavirus Disease 2019
Kameran Mohammed Ali[SUP] 1 [/SUP], Ayad M Ali[SUP] 2 [/SUP], Hassan Mohammad Tawfeeq[SUP] 1 [/SUP], Grazziela Figueredo[SUP] 3 [/SUP], Hassan Muhammad Rostam[SUP] 4 5 [/SUP]
Affiliations
Abstract
Coronavirus disease 2019 (COVID-19) is caused by a contagious virus that has spread to more than 200 countries, territories and regions. Thousands of studies to date have examined all aspects of this disease, yet little is known about the post-recovery status of patients, especially in the long term. Here, we examined erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and serum albumin biomarkers in patients with a history of severe and mild-to-moderate COVID-19 following their recovery. In patients with severe COVID-19, serum albumin had a strong negative correlation with both ESR and CRP level (R[SUP]2[/SUP] = -0.861 and R[SUP]2[/SUP] = -0.711), respectively. Also, there was a positive correlation between ESR and CRP level (R[SUP]2[/SUP] = 0.85) in the same group. However, there was no correlation between these biomarkers among mild-to-moderate COVID-19 patients. In addition, no correlation was recorded between the severe and mild-to-moderate COVID-19 groups. This finding highlights the sustained elevation of ESR and CRP level and reduced serum albumin level that may persist post-recovery in patients with a history of severe COVID-19. This article is protected by copyright. All rights reserved.
Keywords: COVID-19; CRP; ESR; post-recovery; serum albumin.
. 2021 Apr 8.
doi: 10.1002/jmv.27002. Online ahead of print.
Hypoalbuminemia in Patients Following Their Recovery from Severe Coronavirus Disease 2019
Kameran Mohammed Ali[SUP] 1 [/SUP], Ayad M Ali[SUP] 2 [/SUP], Hassan Mohammad Tawfeeq[SUP] 1 [/SUP], Grazziela Figueredo[SUP] 3 [/SUP], Hassan Muhammad Rostam[SUP] 4 5 [/SUP]
Affiliations
- PMID: 33830538
- DOI: 10.1002/jmv.27002
Abstract
Coronavirus disease 2019 (COVID-19) is caused by a contagious virus that has spread to more than 200 countries, territories and regions. Thousands of studies to date have examined all aspects of this disease, yet little is known about the post-recovery status of patients, especially in the long term. Here, we examined erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and serum albumin biomarkers in patients with a history of severe and mild-to-moderate COVID-19 following their recovery. In patients with severe COVID-19, serum albumin had a strong negative correlation with both ESR and CRP level (R[SUP]2[/SUP] = -0.861 and R[SUP]2[/SUP] = -0.711), respectively. Also, there was a positive correlation between ESR and CRP level (R[SUP]2[/SUP] = 0.85) in the same group. However, there was no correlation between these biomarkers among mild-to-moderate COVID-19 patients. In addition, no correlation was recorded between the severe and mild-to-moderate COVID-19 groups. This finding highlights the sustained elevation of ESR and CRP level and reduced serum albumin level that may persist post-recovery in patients with a history of severe COVID-19. This article is protected by copyright. All rights reserved.
Keywords: COVID-19; CRP; ESR; post-recovery; serum albumin.