tetano
Editor, Senior Moderator
J Med Virol
. 2023 Feb 23.
doi: 10.1002/jmv.28594. Online ahead of print.
Ocular Tropism of SARS-CoV-2 Infection
Shuai Zhang[SUP] 1 [/SUP], Jianguo Ju[SUP] 2 [/SUP], Fang Yang[SUP] 2 [/SUP], Chunfu Zheng[SUP] 3 4 [/SUP], Jingbo Zhai[SUP] 1 5 6 [/SUP]
Affiliations
Abstract
SARS-CoV-2, the virus that causes COVID-19, can lead to ocular symptoms such as conjunctivitis and uveitis. Studies suggest that the virus has ocular predisposition and can migrate from the respiratory tract to the eyes via the trigeminal and optic nerves through the brain, leading to ocular infection. However, there is not enough evidence to confirm that the virus can be contracted through the conjunctival route directly in humans. Further research is needed to fully understand the transmission and pathogenesis of SARS-CoV-2 in the eyes. This article is protected by copyright. All rights reserved.
Keywords: Conjunctiva; Immune responses; Infection; Inflammation; Pathogenesis; SARS coronavirus; Virus classification.
. 2023 Feb 23.
doi: 10.1002/jmv.28594. Online ahead of print.
Ocular Tropism of SARS-CoV-2 Infection
Shuai Zhang[SUP] 1 [/SUP], Jianguo Ju[SUP] 2 [/SUP], Fang Yang[SUP] 2 [/SUP], Chunfu Zheng[SUP] 3 4 [/SUP], Jingbo Zhai[SUP] 1 5 6 [/SUP]
Affiliations
- PMID: 36815509
- DOI: 10.1002/jmv.28594
Abstract
SARS-CoV-2, the virus that causes COVID-19, can lead to ocular symptoms such as conjunctivitis and uveitis. Studies suggest that the virus has ocular predisposition and can migrate from the respiratory tract to the eyes via the trigeminal and optic nerves through the brain, leading to ocular infection. However, there is not enough evidence to confirm that the virus can be contracted through the conjunctival route directly in humans. Further research is needed to fully understand the transmission and pathogenesis of SARS-CoV-2 in the eyes. This article is protected by copyright. All rights reserved.
Keywords: Conjunctiva; Immune responses; Infection; Inflammation; Pathogenesis; SARS coronavirus; Virus classification.