tetano
Editor, Senior Moderator
J Med Virol
. 2021 Jul 14.
doi: 10.1002/jmv.27202. Online ahead of print.
Probable viremia and positive placental swabs for SARS-CoV-2 in a preterm pregnant woman with mild COVID-19
Yesim Akdemir[SUP] 1 [/SUP], Demet Haciseyitoglu[SUP] 2 [/SUP], Guven Celebi[SUP] 3 [/SUP], Cumhur Aydemir[SUP] 4 [/SUP], Burak Bahadır[SUP] 5 [/SUP], Anil Turhan Cakir[SUP] 1 [/SUP], Aykut Barut[SUP] 1 [/SUP], Ulku Ozmen[SUP] 1 [/SUP]
Affiliations
Abstract
Objective: This study aimed to report a case of mild novel coronavirus disease (COVID-19) in a pregnant woman with probable viremia, as reverse transcription polymerase chain reaction (RT-PCR) testing of endometrial and placental swabs for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was positive.
Case report: We present the case of a 26-year-old multigravida at 35 weeks 2 days of gestation, who had extensive thigh and abdominal cellulitis, and was tested SARS-CoV-2 positive by RT-PCR performed on samples from the endometrium and maternal side of the placenta. However, other samples (amniotic fluid, fetal side of the placenta, umbilical cord, maternal vagina, and neonatal nasopharynx) tested negative for SARS-CoV-2.
Conclusion: This is one of the rare reports of probable SARS-CoV-2 viremia with the presence of SARS-CoV-2 in the endometrium and placenta, but not leading to vertical transmission and neonatal infection. Knowledge about transplacental transmission and results are very limited. More RT-PCR tests on placental and cord blood samples are needed in order to safely make definite conclusions. This article is protected by copyright. All rights reserved.
Keywords: COVID-19; SARS-CoV-2; placenta; pregnancy; vertical transmission.
. 2021 Jul 14.
doi: 10.1002/jmv.27202. Online ahead of print.
Probable viremia and positive placental swabs for SARS-CoV-2 in a preterm pregnant woman with mild COVID-19
Yesim Akdemir[SUP] 1 [/SUP], Demet Haciseyitoglu[SUP] 2 [/SUP], Guven Celebi[SUP] 3 [/SUP], Cumhur Aydemir[SUP] 4 [/SUP], Burak Bahadır[SUP] 5 [/SUP], Anil Turhan Cakir[SUP] 1 [/SUP], Aykut Barut[SUP] 1 [/SUP], Ulku Ozmen[SUP] 1 [/SUP]
Affiliations
- PMID: 34260081
- DOI: 10.1002/jmv.27202
Abstract
Objective: This study aimed to report a case of mild novel coronavirus disease (COVID-19) in a pregnant woman with probable viremia, as reverse transcription polymerase chain reaction (RT-PCR) testing of endometrial and placental swabs for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was positive.
Case report: We present the case of a 26-year-old multigravida at 35 weeks 2 days of gestation, who had extensive thigh and abdominal cellulitis, and was tested SARS-CoV-2 positive by RT-PCR performed on samples from the endometrium and maternal side of the placenta. However, other samples (amniotic fluid, fetal side of the placenta, umbilical cord, maternal vagina, and neonatal nasopharynx) tested negative for SARS-CoV-2.
Conclusion: This is one of the rare reports of probable SARS-CoV-2 viremia with the presence of SARS-CoV-2 in the endometrium and placenta, but not leading to vertical transmission and neonatal infection. Knowledge about transplacental transmission and results are very limited. More RT-PCR tests on placental and cord blood samples are needed in order to safely make definite conclusions. This article is protected by copyright. All rights reserved.
Keywords: COVID-19; SARS-CoV-2; placenta; pregnancy; vertical transmission.