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J Med Virol . Questions concerning the proximal origin of SARS-CoV-2

tetano

Editor, Senior Moderator
J Med Virol


. 2020 Sep 3.
doi: 10.1002/jmv.26478. Online ahead of print.
Questions concerning the proximal origin of SARS-CoV-2


Murat Seyran[SUP] 1 2 [/SUP], Damiano Pizzol[SUP] 3 [/SUP], Parise Adadi[SUP] 4 [/SUP], Tarek Mohamed Abd El-Aziz[SUP] 5 6 [/SUP], Sk Sarif Hassan[SUP] 7 [/SUP], Antonio Soares[SUP] 5 [/SUP], Ramesh Kandimalla[SUP] 8 9 [/SUP], Kenneth Lundstrom[SUP] 10 [/SUP], Murtaza Tambuwala[SUP] 11 [/SUP], Alaa A A Aljabali[SUP] 12 [/SUP], Amos Lal[SUP] 13 [/SUP], Gajendra Kumar Azad[SUP] 14 [/SUP], Pabitra Pal Choudhury[SUP] 15 [/SUP], Vladimir N Uversky[SUP] 16 [/SUP], Samendra P Sherchan[SUP] 17 [/SUP], Bruce D Uhal[SUP] 18 [/SUP], Nima Rezaei[SUP] 19 20 [/SUP], Adam M Brufsky[SUP] 21 [/SUP]



Affiliations

Abstract

There is a consensus that Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) originated naturally from Bat coronaviruses (CoVs), in particular RaTG13. However, the SARS-CoV-2 host tropism/adaptation pattern has significant discrepancies compared to other CoVs, raising questions concerning the proximal origin of SARS-CoV-2. This article is protected by copyright. All rights reserved.

Keywords: Coronavirus; Fusion Protein; Genetic Variability; Mutation.
 
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