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J Microbiol Immunol Infect . Desaturation and heme elevation during COVID-19 infection: A potential prognostic factor of heme oxygenase-1

tetano

Editor, Senior Moderator
J Microbiol Immunol Infect


. 2020 Oct 16;S1684-1182(20)30246-2.
doi: 10.1016/j.jmii.2020.10.001. Online ahead of print.
Desaturation and heme elevation during COVID-19 infection: A potential prognostic factor of heme oxygenase-1


Wen-Lin Su[SUP] 1 [/SUP], Chih-Pei Lin[SUP] 2 [/SUP], Hui-Ching Hang[SUP] 3 [/SUP], Ping-Sheng Wu[SUP] 4 [/SUP], Ching-Feng Cheng[SUP] 4 [/SUP], You-Chen Chao[SUP] 5 [/SUP]



Affiliations

Abstract

Increased heme levels, anemia, and desaturation occur during infection. We aimed to compare the levels of heme, heme oxygenase-1 (HO-1), ferritin, and bilirubin in coronavirus disease 2019 (COVID-19) patients at different saturation levels. Heme and HO-1 enzyme levels significantly increased in the low SpO[SUB]2[/SUB] group, but further studies are required.

Keywords: COVID-19; Heme; Heme oxygenase-1; SARS-CoV-2.
 
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