tetano
Editor, Senior Moderator
J Multidiscip Healthc
. 2020 Oct 6;13:1089-1097.
doi: 10.2147/JMDH.S273918. eCollection 2020.
Clinical Characteristics and Outcomes Among COVID-19 Hospitalized Patients with Chronic Conditions: A Retrospective Single-Center Study
Ziyad Saeed Almalki[SUP] 1 [/SUP], Mohd Faiyaz Khan[SUP] 1 [/SUP], Saja Almazrou[SUP] 2 [/SUP], Abdullah Salah Alanazi[SUP] 3 [/SUP], Mohammed Shahid Iqbal[SUP] 1 [/SUP], Abdulhadi Alqahtani[SUP] 4 [/SUP], Saleh Alghamdi[SUP] 4 [/SUP], Abdullah K Alahmari[SUP] 1 [/SUP]
Affiliations
Abstract
Purpose: Evidence to date suggests that having chronic conditions increases the probability of severe illness from severe coronavirus disease 2019 (COVID-19). Thus, it is essential to identify the features of those patients. The purpose of this research was to identify the clinical characteristics and outcomes of COVID-19 patients with chronic conditions.
Patients and methods: A retrospective cross-sectional single-center study was conducted using electronic medical records of hospitalized COVID-19 patients between March 1, 2020, and May 20, 2020. Patients' basic information, laboratory test, clinical data, medications, and outcome data have been extracted and compared among three groups: patients without chronic conditions, patients with one chronic condition, and patients with two or more chronic conditions. Chi-square, Fisher's exact test, Student's t-test, and the Mann-Whitney U-test were used.
Results: The study population was 458 patients, with an average age of 38.8 years (standard deviation (SD) 12.8). There were 398 (86.9%) males in the study population, most of them with one chronic condition. There were 14 (14.3%) smokers, and the majority of them were among patients with two or more chronic conditions. Longer hospital stay and time in the intensive care unit (ICU), a higher probability of ICU admission, and the need for mechanical ventilation were identified among patients with two or more chronic conditions. Dyspnea, an increased level of platelet counts, and a reduction in hemoglobin levels were discovered among patients with two or more chronic conditions.
Conclusion: Patients with more chronic conditions were at higher risk of yielding poor clinical outcomes. Prevention and treatment of infections in these patients merit more attention.
Keywords: chronic conditions; clinical features; coronavirus disease 2019; outcomes.
. 2020 Oct 6;13:1089-1097.
doi: 10.2147/JMDH.S273918. eCollection 2020.
Clinical Characteristics and Outcomes Among COVID-19 Hospitalized Patients with Chronic Conditions: A Retrospective Single-Center Study
Ziyad Saeed Almalki[SUP] 1 [/SUP], Mohd Faiyaz Khan[SUP] 1 [/SUP], Saja Almazrou[SUP] 2 [/SUP], Abdullah Salah Alanazi[SUP] 3 [/SUP], Mohammed Shahid Iqbal[SUP] 1 [/SUP], Abdulhadi Alqahtani[SUP] 4 [/SUP], Saleh Alghamdi[SUP] 4 [/SUP], Abdullah K Alahmari[SUP] 1 [/SUP]
Affiliations
- PMID: 33116555
- PMCID: PMC7547771
- DOI: 10.2147/JMDH.S273918
Abstract
Purpose: Evidence to date suggests that having chronic conditions increases the probability of severe illness from severe coronavirus disease 2019 (COVID-19). Thus, it is essential to identify the features of those patients. The purpose of this research was to identify the clinical characteristics and outcomes of COVID-19 patients with chronic conditions.
Patients and methods: A retrospective cross-sectional single-center study was conducted using electronic medical records of hospitalized COVID-19 patients between March 1, 2020, and May 20, 2020. Patients' basic information, laboratory test, clinical data, medications, and outcome data have been extracted and compared among three groups: patients without chronic conditions, patients with one chronic condition, and patients with two or more chronic conditions. Chi-square, Fisher's exact test, Student's t-test, and the Mann-Whitney U-test were used.
Results: The study population was 458 patients, with an average age of 38.8 years (standard deviation (SD) 12.8). There were 398 (86.9%) males in the study population, most of them with one chronic condition. There were 14 (14.3%) smokers, and the majority of them were among patients with two or more chronic conditions. Longer hospital stay and time in the intensive care unit (ICU), a higher probability of ICU admission, and the need for mechanical ventilation were identified among patients with two or more chronic conditions. Dyspnea, an increased level of platelet counts, and a reduction in hemoglobin levels were discovered among patients with two or more chronic conditions.
Conclusion: Patients with more chronic conditions were at higher risk of yielding poor clinical outcomes. Prevention and treatment of infections in these patients merit more attention.
Keywords: chronic conditions; clinical features; coronavirus disease 2019; outcomes.