tetano
Editor, Senior Moderator
J Obstet Gynaecol Res
. 2023 Jun 24.
doi: 10.1111/jog.15725. Online ahead of print. Evaluation of fetal adrenal artery Doppler velocimetry and fetal adrenal gland size in pregnancies after recovery from COVID-19
Derya Uyan Hendem[SUP] 1 2 [/SUP], Deniz Oluklu[SUP] 1 2 [/SUP], Dilek Menekse Beser[SUP] 1 2 [/SUP], Muradiye Yildirim[SUP] 1 2 [/SUP], Bedri Sakcak[SUP] 1 2 [/SUP], Ezgi Turgut[SUP] 1 2 [/SUP], Dilek Sahin[SUP] 3 4 [/SUP]
Affiliations
Aim: Assessment of the fetal adrenal gland (FAG) size and middle adrenal artery (MAA) Doppler parameters in pregnancy recovered from Coronavirus Disease (COVID-19) and comparison of the values with the healthy control group.
Methods: Thirty-eight pregnant women who had recovered from COVID-19 infection and 76 healthy control group between 33 and 35 weeks of gestation were involved in this case-control study. Fetuses were examined for fetal biometry, fetal well-being, adrenal gland dimensions, and Doppler parameters 4-6 weeks after the diagnosis of COVID 19 infection. FAG dimensions were measured in two planes and MAA blood flow velocity was evaluated with pulsed Doppler. Pregnant women with COVID-19 infection were grouped according to the National Institutes of Health for the severity of the disease, and those with mild and moderate infections were examined in the study.
Results: The total adrenal gland (TAG) height, fetal zone (FZ) length and width, and MAA-Peak Systolic Velocity (MAA-PSV) were significantly higher, and the MAA-Pulsatility Index (MAA-PI) was significantly lower in the COVID-19 group (p < 0.05). The lower in MAA-PI and the higher in MAA-PSV, the width of the FZ, and width of the TAG were found to be significant in the moderate group compared to the mild groups (p < 0.05).
Conclusion: COVID-19 pregnancies might cause early maturation of the FAG and its vasculature depends on the intrauterine stress due to the hyper-inflammation, so fetuses exposed to maternal COVID-19 suggested to have an increase in blood flow to the adrenal gland and fetal adrenal size.
Keywords: COVID-19; SARS-CoV-2; fetal adrenal artery Doppler; fetal adrenal gland size.
. 2023 Jun 24.
doi: 10.1111/jog.15725. Online ahead of print. Evaluation of fetal adrenal artery Doppler velocimetry and fetal adrenal gland size in pregnancies after recovery from COVID-19
Derya Uyan Hendem[SUP] 1 2 [/SUP], Deniz Oluklu[SUP] 1 2 [/SUP], Dilek Menekse Beser[SUP] 1 2 [/SUP], Muradiye Yildirim[SUP] 1 2 [/SUP], Bedri Sakcak[SUP] 1 2 [/SUP], Ezgi Turgut[SUP] 1 2 [/SUP], Dilek Sahin[SUP] 3 4 [/SUP]
Affiliations
- PMID: 37354108
- DOI: 10.1111/jog.15725
Aim: Assessment of the fetal adrenal gland (FAG) size and middle adrenal artery (MAA) Doppler parameters in pregnancy recovered from Coronavirus Disease (COVID-19) and comparison of the values with the healthy control group.
Methods: Thirty-eight pregnant women who had recovered from COVID-19 infection and 76 healthy control group between 33 and 35 weeks of gestation were involved in this case-control study. Fetuses were examined for fetal biometry, fetal well-being, adrenal gland dimensions, and Doppler parameters 4-6 weeks after the diagnosis of COVID 19 infection. FAG dimensions were measured in two planes and MAA blood flow velocity was evaluated with pulsed Doppler. Pregnant women with COVID-19 infection were grouped according to the National Institutes of Health for the severity of the disease, and those with mild and moderate infections were examined in the study.
Results: The total adrenal gland (TAG) height, fetal zone (FZ) length and width, and MAA-Peak Systolic Velocity (MAA-PSV) were significantly higher, and the MAA-Pulsatility Index (MAA-PI) was significantly lower in the COVID-19 group (p < 0.05). The lower in MAA-PI and the higher in MAA-PSV, the width of the FZ, and width of the TAG were found to be significant in the moderate group compared to the mild groups (p < 0.05).
Conclusion: COVID-19 pregnancies might cause early maturation of the FAG and its vasculature depends on the intrauterine stress due to the hyper-inflammation, so fetuses exposed to maternal COVID-19 suggested to have an increase in blood flow to the adrenal gland and fetal adrenal size.
Keywords: COVID-19; SARS-CoV-2; fetal adrenal artery Doppler; fetal adrenal gland size.