tetano
Editor, Senior Moderator
J Pediatr
. 2022 Apr 18;S0022-3476(22)00346-8.
doi: 10.1016/j.jpeds.2022.04.031. Online ahead of print.
Acute Necrotizing Encephalopathy Associated with Coronavirus Disease 2019 in an Infant
Mariha Khan[SUP] 1 [/SUP], Samhita Bhattarai[SUP] 1 [/SUP], Thomas G Boyce[SUP] 1 [/SUP], Reyaad A Hayek[SUP] 2 [/SUP], Sergey I Zhadanov[SUP] 2 [/SUP], Elisabeth E Hooper[SUP] 1 [/SUP], Edward G Fernandez[SUP] 1 [/SUP], Monica A Koehn[SUP] 3 [/SUP]
Affiliations
Abstract
A 5-week-old infant born at term was diagnosed with acute necrotizing encephalopathy associated with SARS-CoV-2 as evidenced by clinical presentation, neuroimaging, and cerebrospinal fluid studies. Our patient was treated with high dose intravenous methylprednisolone, tocilizumab and intravenous immunoglobulin with significant short-term clinical improvement but long-term sequelae.
. 2022 Apr 18;S0022-3476(22)00346-8.
doi: 10.1016/j.jpeds.2022.04.031. Online ahead of print.
Acute Necrotizing Encephalopathy Associated with Coronavirus Disease 2019 in an Infant
Mariha Khan[SUP] 1 [/SUP], Samhita Bhattarai[SUP] 1 [/SUP], Thomas G Boyce[SUP] 1 [/SUP], Reyaad A Hayek[SUP] 2 [/SUP], Sergey I Zhadanov[SUP] 2 [/SUP], Elisabeth E Hooper[SUP] 1 [/SUP], Edward G Fernandez[SUP] 1 [/SUP], Monica A Koehn[SUP] 3 [/SUP]
Affiliations
- PMID: 35447125
- DOI: 10.1016/j.jpeds.2022.04.031
Abstract
A 5-week-old infant born at term was diagnosed with acute necrotizing encephalopathy associated with SARS-CoV-2 as evidenced by clinical presentation, neuroimaging, and cerebrospinal fluid studies. Our patient was treated with high dose intravenous methylprednisolone, tocilizumab and intravenous immunoglobulin with significant short-term clinical improvement but long-term sequelae.