tetano
Editor, Senior Moderator
J Pediatr Hematol Oncol
. 2022 Oct 3.
doi: 10.1097/MPH.0000000000002559. Online ahead of print.
Influenza Vaccination Receipt in Pediatric Patients With Cancer or Sickle Cell Disease
J Nathan Yarnall[SUP] 1 2 [/SUP], Ann Mertens[SUP] 1 2 [/SUP], Marianne Yee[SUP] 1 2 [/SUP], Evan Orenstein[SUP] 1 [/SUP], Kristina W Lai[SUP] 2 [/SUP], Karen Wasilewski-Masker[SUP] 1 2 [/SUP]
Affiliations
Abstract
Background: Influenza causes greater morbidity in children with cancer or sickle cell disease (SCD). Literature on influenza vaccination receipt for these populations is limited in low-vaccination states. Outpatient interventions improve vaccine receipt but isolated inpatient interventions remain unstudied.
Procedure: We reviewed influenza vaccine receipt of children with cancer or SCD treated at Children's Healthcare of Atlanta during three influenza seasons. We implemented a clinical decision support intervention during an influenza season and compared influenza vaccine receipt preintervention and postintervention among admitted children.
Results: The oncology cohort (N=1548, 60% to 62%) and the SCD cohort (N=2549, 61% to 65%) had similar-to-higher vaccination receipt to the United States (58% to 64%, P=0.01 to 0.79) and Georgia (51% to 56%, P<0.01). The intervention did not significantly improve vaccination receipt for admitted children with cancer (40% vs. 56%, P=0.05 to 0.88) or SCD (44% vs. 56%, P=0.01). Regression modeling also found no significant increase in vaccine receipt (hematologic malignancy: 0.8 [0.73 to 0.98], solid tumor: 0.9 [0.80 to 1.90], central nervous system tumor: 0.9 [0.71 to 1.14], SCD: 0.9 [0.85 to 0.99]).
Conclusions: Children with cancer and SCD have similar-to-greater influenza vaccination receipt compared with Georgia and the United States. An inpatient intervention did not significantly improve influenza vaccine receipt in these patient cohorts. Future studies are needed to identify alternative approaches to improving vaccine receipt in these cohorts.
. 2022 Oct 3.
doi: 10.1097/MPH.0000000000002559. Online ahead of print.
Influenza Vaccination Receipt in Pediatric Patients With Cancer or Sickle Cell Disease
J Nathan Yarnall[SUP] 1 2 [/SUP], Ann Mertens[SUP] 1 2 [/SUP], Marianne Yee[SUP] 1 2 [/SUP], Evan Orenstein[SUP] 1 [/SUP], Kristina W Lai[SUP] 2 [/SUP], Karen Wasilewski-Masker[SUP] 1 2 [/SUP]
Affiliations
- PMID: 36219461
- DOI: 10.1097/MPH.0000000000002559
Abstract
Background: Influenza causes greater morbidity in children with cancer or sickle cell disease (SCD). Literature on influenza vaccination receipt for these populations is limited in low-vaccination states. Outpatient interventions improve vaccine receipt but isolated inpatient interventions remain unstudied.
Procedure: We reviewed influenza vaccine receipt of children with cancer or SCD treated at Children's Healthcare of Atlanta during three influenza seasons. We implemented a clinical decision support intervention during an influenza season and compared influenza vaccine receipt preintervention and postintervention among admitted children.
Results: The oncology cohort (N=1548, 60% to 62%) and the SCD cohort (N=2549, 61% to 65%) had similar-to-higher vaccination receipt to the United States (58% to 64%, P=0.01 to 0.79) and Georgia (51% to 56%, P<0.01). The intervention did not significantly improve vaccination receipt for admitted children with cancer (40% vs. 56%, P=0.05 to 0.88) or SCD (44% vs. 56%, P=0.01). Regression modeling also found no significant increase in vaccine receipt (hematologic malignancy: 0.8 [0.73 to 0.98], solid tumor: 0.9 [0.80 to 1.90], central nervous system tumor: 0.9 [0.71 to 1.14], SCD: 0.9 [0.85 to 0.99]).
Conclusions: Children with cancer and SCD have similar-to-greater influenza vaccination receipt compared with Georgia and the United States. An inpatient intervention did not significantly improve influenza vaccine receipt in these patient cohorts. Future studies are needed to identify alternative approaches to improving vaccine receipt in these cohorts.