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J Pediatr . Immature platelet fraction as a biomarker for disease severity in pediatric respiratory Coronavirus Disease 2019

tetano

Editor, Senior Moderator
J Pediatr


. 2022 Aug 6;S0022-3476(22)00703-X.
doi: 10.1016/j.jpeds.2022.07.035. Online ahead of print.
Immature platelet fraction as a biomarker for disease severity in pediatric respiratory Coronavirus Disease 2019


Nicholas Cj Lee[SUP] 1 [/SUP], Yusuf Kemal Demir[SUP] 2 [/SUP], Bilal Ashraf[SUP] 1 [/SUP], Ibrahim Ibrahim[SUP] 3 [/SUP], Taha Bat[SUP] 3 [/SUP], Kathryn E Dickerson[SUP] 4 [/SUP]



Affiliations

Abstract

In this retrospective single-institution cohort study of 113 hospitalized pediatric patients with respiratory Coronavirus Disease 2019 (COVID-19), those admitted to the intensive care unit or requiring mechanical ventilation had significantly higher immature platelet fractions (IPF) than those who did not require ICU-level care or ventilation. IPF may be an accessible biomarker for disease severity in pediatric respiratory COVID-19.

Keywords: COVID-19; SARS-CoV-2; biomarker; immature platelet; pediatric.
 
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