tetano
Editor, Senior Moderator
J Public Health Res
. 2021 Apr 19.
doi: 10.4081/jphr.2021.2270. Online ahead of print.
CT findings of COVID-19 pneumonia in ICU-patients
Riccardo Cau[SUP] 1 [/SUP], Zeno Falaschi[SUP] 2 [/SUP], Alessio Pasch?[SUP] 3 [/SUP], Pietro Danna[SUP] 4 [/SUP], Roberto Arioli[SUP] 5 [/SUP], Chiara D Arru[SUP] 6 [/SUP], Domenico Zagaria[SUP] 7 [/SUP], Stefano Tricca[SUP] 8 [/SUP], Jasjit S Suri[SUP] 9 [/SUP], Mannudeep K Karla[SUP] 10 [/SUP], Alessandro Carriero[SUP] 11 [/SUP], Luca Saba[SUP] 12 [/SUP]
Affiliations
Abstract
Background: In December 2019, a cluster of unknown etiology pneumonia cases occurred in Wuhan, China leading to identification of the responsible pathogen as SARS-coV-2. Since then, the coronavirus disease 2019 (COVID-19) has spread to the entire world. Computed Tomography (CT) is frequently used to assess severity and complications of COVID-19 pneumonia. The purpose of this study is to compare the CT patterns and clinical characteristics in intensive care unit (ICU) and non-ICU patients with COVID-19 pneumonia.
Design and methods: This retrospective study included 218 consecutive patients (136 males; 82 females; mean age 63?15 years) with laboratory-confirmed SARS-coV-2. Patients were categorized in two different groups: (a) ICU patients and (b) non-ICU inpatients. We assessed the type and extent of pulmonary opacities on chest CT exams and recorded the information on comorbidities and laboratory values for all patients.
Results: Of the 218 patients, 23 (20 males: 3 females; mean age 60 years) required ICU admission, 195 (118 males: 77 females, mean age 64 years) were admitted to a clinical ward. Compared with non-ICU patients, ICU patients were predominantly males (60% versus 83% p=0.03), had more comorbidities, a positive CRP (p=0.04) and higher LDH values (p=0.008). ICU patients' chest CT demonstrated higher incidence of consolidation (p=0.03), mixed lesions (p=0.01), bilateral opacities (p<0.01) and overall greater lung involvement by consolidation (p=0.02) and GGO (p=0.001).
Conclusions: CT imaging features of ICU patients affected by COVID-19 are significantly different compared with non-ICU patients. Identification of CT features could assist in a stratification of the disease severity and supportive treatment.
. 2021 Apr 19.
doi: 10.4081/jphr.2021.2270. Online ahead of print.
CT findings of COVID-19 pneumonia in ICU-patients
Riccardo Cau[SUP] 1 [/SUP], Zeno Falaschi[SUP] 2 [/SUP], Alessio Pasch?[SUP] 3 [/SUP], Pietro Danna[SUP] 4 [/SUP], Roberto Arioli[SUP] 5 [/SUP], Chiara D Arru[SUP] 6 [/SUP], Domenico Zagaria[SUP] 7 [/SUP], Stefano Tricca[SUP] 8 [/SUP], Jasjit S Suri[SUP] 9 [/SUP], Mannudeep K Karla[SUP] 10 [/SUP], Alessandro Carriero[SUP] 11 [/SUP], Luca Saba[SUP] 12 [/SUP]
Affiliations
- PMID: 33876627
- DOI: 10.4081/jphr.2021.2270
Abstract
Background: In December 2019, a cluster of unknown etiology pneumonia cases occurred in Wuhan, China leading to identification of the responsible pathogen as SARS-coV-2. Since then, the coronavirus disease 2019 (COVID-19) has spread to the entire world. Computed Tomography (CT) is frequently used to assess severity and complications of COVID-19 pneumonia. The purpose of this study is to compare the CT patterns and clinical characteristics in intensive care unit (ICU) and non-ICU patients with COVID-19 pneumonia.
Design and methods: This retrospective study included 218 consecutive patients (136 males; 82 females; mean age 63?15 years) with laboratory-confirmed SARS-coV-2. Patients were categorized in two different groups: (a) ICU patients and (b) non-ICU inpatients. We assessed the type and extent of pulmonary opacities on chest CT exams and recorded the information on comorbidities and laboratory values for all patients.
Results: Of the 218 patients, 23 (20 males: 3 females; mean age 60 years) required ICU admission, 195 (118 males: 77 females, mean age 64 years) were admitted to a clinical ward. Compared with non-ICU patients, ICU patients were predominantly males (60% versus 83% p=0.03), had more comorbidities, a positive CRP (p=0.04) and higher LDH values (p=0.008). ICU patients' chest CT demonstrated higher incidence of consolidation (p=0.03), mixed lesions (p=0.01), bilateral opacities (p<0.01) and overall greater lung involvement by consolidation (p=0.02) and GGO (p=0.001).
Conclusions: CT imaging features of ICU patients affected by COVID-19 are significantly different compared with non-ICU patients. Identification of CT features could assist in a stratification of the disease severity and supportive treatment.