tetano
Editor, Senior Moderator
J Res Med Sci
. 2021 Jun 30;26:40.
doi: 10.4103/jrms.JRMS_1012_20. eCollection 2021.
Mortality and characteristics of older people dying with COVID-19 in Lombardy nursing homes, Italy: An observational cohort study
Chiara Arienti[SUP] 1 [/SUP], Lorenzo Brambilla[SUP] 1 [/SUP], Silvia Campagnini[SUP] 2 3 [/SUP], Chiara Fanciullacci[SUP] 2 [/SUP], Fabrizio Giunco[SUP] 1 [/SUP], Andrea Mannini[SUP] 2 3 [/SUP], Michele Patrini[SUP] 1 [/SUP], Federica Tartarone[SUP] 1 [/SUP], Maria Chiara Carrozza[SUP] 1 3 [/SUP]
Affiliations
Abstract
Background: The aim of the study was to describe the epidemiological characteristics of Nursing Homes (NHs) residents infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and to compute the related case-fatality rate.
Materials and methods: The outcomes were mortality and case-fatality rate with related epidemiological characteristics (age, sex, comorbidity, and frailty).
Results: During the COVID-19 outbreak lasted from March 1 to May 7, 2020, 330 residents died in Fondazione Don Gnocchi NHs bringing the mortality rate to 27% with a dramatic increase compared to the same period of 2019, when it was 7.5%. Naso/oropharyngeal swabs resulted positive for COVID-19 in 315 (71%) of the 441of the symptomatic/exposed residents tested. The COVID-19 population was 75% female, with a 17% overall fatality rate and sex-specific fatality rates of 19% and 13% for females and males, respectively. Fifty-six percent of deaths presented SARS-CoV-2-associated pneumonia, 15% cardiovascular, and 29% miscellaneous pathologies.
Conclusion: Patients' complexity and frailty might influence SARS-CoV-2 infection case-fatality rate estimates. A COVID-19 register is needed to study COVID-19 frail patients' epidemiology and characteristics.
Keywords: COVID-19; epidemiology; frail elderly; mortality; nursing homes.
. 2021 Jun 30;26:40.
doi: 10.4103/jrms.JRMS_1012_20. eCollection 2021.
Mortality and characteristics of older people dying with COVID-19 in Lombardy nursing homes, Italy: An observational cohort study
Chiara Arienti[SUP] 1 [/SUP], Lorenzo Brambilla[SUP] 1 [/SUP], Silvia Campagnini[SUP] 2 3 [/SUP], Chiara Fanciullacci[SUP] 2 [/SUP], Fabrizio Giunco[SUP] 1 [/SUP], Andrea Mannini[SUP] 2 3 [/SUP], Michele Patrini[SUP] 1 [/SUP], Federica Tartarone[SUP] 1 [/SUP], Maria Chiara Carrozza[SUP] 1 3 [/SUP]
Affiliations
- PMID: 34484372
- PMCID: PMC8384010
- DOI: 10.4103/jrms.JRMS_1012_20
Abstract
Background: The aim of the study was to describe the epidemiological characteristics of Nursing Homes (NHs) residents infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and to compute the related case-fatality rate.
Materials and methods: The outcomes were mortality and case-fatality rate with related epidemiological characteristics (age, sex, comorbidity, and frailty).
Results: During the COVID-19 outbreak lasted from March 1 to May 7, 2020, 330 residents died in Fondazione Don Gnocchi NHs bringing the mortality rate to 27% with a dramatic increase compared to the same period of 2019, when it was 7.5%. Naso/oropharyngeal swabs resulted positive for COVID-19 in 315 (71%) of the 441of the symptomatic/exposed residents tested. The COVID-19 population was 75% female, with a 17% overall fatality rate and sex-specific fatality rates of 19% and 13% for females and males, respectively. Fifty-six percent of deaths presented SARS-CoV-2-associated pneumonia, 15% cardiovascular, and 29% miscellaneous pathologies.
Conclusion: Patients' complexity and frailty might influence SARS-CoV-2 infection case-fatality rate estimates. A COVID-19 register is needed to study COVID-19 frail patients' epidemiology and characteristics.
Keywords: COVID-19; epidemiology; frail elderly; mortality; nursing homes.