tetano
Editor, Senior Moderator
J Res Med Sci
. 2021 Nov 29;26:112.
doi: 10.4103/jrms.JRMS_1151_20. eCollection 2021.
Serum level of Vitamin D is associated with COVID-19 mortality rate in hospitalized patients
Mitra Ranjbar[SUP] 1 [/SUP], Mohammad Hadi Karbalaie Niya[SUP] 2 [/SUP], Maryam Roham[SUP] 1 3 [/SUP], Nader Rezaie[SUP] 4 [/SUP], Mahdi Yadollahzadeh[SUP] 5 [/SUP], Mohsen Farrokhpour[SUP] 5 [/SUP], Mehdi Azimi[SUP] 5 [/SUP], Nima Motamed[SUP] 6 [/SUP], Dhayaneethie Perumal[SUP] 7 [/SUP], Fahimeh Safarnezhad Tameshkel[SUP] 2 [/SUP], Farahnaz Dadras[SUP] 8 [/SUP], Nahid Hashemi Madani[SUP] 9 [/SUP], Behrooz Ghanbari[SUP] 2 [/SUP], Amirhossein Faraji[SUP] 2 [/SUP], Mehdi Nikkhah[SUP] 2 [/SUP], Shahrzad Rahmani[SUP] 8 [/SUP], Fatemah Golgiri[SUP] 9 [/SUP], Seyed Yadollah Emadi[SUP] 2 [/SUP], Rowshanak Abbasi[SUP] 9 [/SUP], Iman Mohseni[SUP] 10 [/SUP], Mohammad Reza Babaei[SUP] 10 [/SUP], Ramin Eskandari[SUP] 11 [/SUP], Manizhe Ataee[SUP] 10 [/SUP], Mahshid Panahi[SUP] 2 [/SUP], Farhad Zamani[SUP] 2 [/SUP], Mahin Jamshidi Makiani[SUP] 1 3 [/SUP], Azadeh Laali[SUP] 1 3 [/SUP]
Affiliations
Abstract
Background: Due to widespread of coronavirus disease 2019 (COVID-19) infection, identification of its risk factors and clinical characteristics are important. The aim of the present study was to assess Vitamin D levels in individuals with severe acute respiratory syndrome coronavirus-19 infection and to report on its potential as a predictive marker.
Materials and methods: All patients, diagnosed with COVID-19 infection from February 16 to March 21, 2020, and referred to Firoozgar Hospital, Tehran, Iran, were enrolled in this study. Vitamin D analysis was undertaken on patient serum samples using a commercial kit (Pars Azmoon Co., Tehran, Iran). SPSS v. 22 was used for statistical analysis.
Results: Vitamin D serum concentration was analyzed in a total of 317 patients whose mean age ± standard deviation was 62.05 ± 15 years and with 62.5% being male. A significant association of Vitamin D level and death was observed. Higher levels of serum Vitamin D had protection against death (odds ratio = 0.955 [95% confidence interval = 0.923-0.988], P = 0.008).
Conclusion: As a preliminary study in the Iranian population who suffered COVID-19 disease, we identified that Vitamin D deficiency was associated with a higher death rate and intensive care unit admission.
Keywords: Coronavirus disease 2019; Vitamin D; malnutrition; respiratory tract infection.
. 2021 Nov 29;26:112.
doi: 10.4103/jrms.JRMS_1151_20. eCollection 2021.
Serum level of Vitamin D is associated with COVID-19 mortality rate in hospitalized patients
Mitra Ranjbar[SUP] 1 [/SUP], Mohammad Hadi Karbalaie Niya[SUP] 2 [/SUP], Maryam Roham[SUP] 1 3 [/SUP], Nader Rezaie[SUP] 4 [/SUP], Mahdi Yadollahzadeh[SUP] 5 [/SUP], Mohsen Farrokhpour[SUP] 5 [/SUP], Mehdi Azimi[SUP] 5 [/SUP], Nima Motamed[SUP] 6 [/SUP], Dhayaneethie Perumal[SUP] 7 [/SUP], Fahimeh Safarnezhad Tameshkel[SUP] 2 [/SUP], Farahnaz Dadras[SUP] 8 [/SUP], Nahid Hashemi Madani[SUP] 9 [/SUP], Behrooz Ghanbari[SUP] 2 [/SUP], Amirhossein Faraji[SUP] 2 [/SUP], Mehdi Nikkhah[SUP] 2 [/SUP], Shahrzad Rahmani[SUP] 8 [/SUP], Fatemah Golgiri[SUP] 9 [/SUP], Seyed Yadollah Emadi[SUP] 2 [/SUP], Rowshanak Abbasi[SUP] 9 [/SUP], Iman Mohseni[SUP] 10 [/SUP], Mohammad Reza Babaei[SUP] 10 [/SUP], Ramin Eskandari[SUP] 11 [/SUP], Manizhe Ataee[SUP] 10 [/SUP], Mahshid Panahi[SUP] 2 [/SUP], Farhad Zamani[SUP] 2 [/SUP], Mahin Jamshidi Makiani[SUP] 1 3 [/SUP], Azadeh Laali[SUP] 1 3 [/SUP]
Affiliations
- PMID: 35126575
- PMCID: PMC8765512
- DOI: 10.4103/jrms.JRMS_1151_20
Abstract
Background: Due to widespread of coronavirus disease 2019 (COVID-19) infection, identification of its risk factors and clinical characteristics are important. The aim of the present study was to assess Vitamin D levels in individuals with severe acute respiratory syndrome coronavirus-19 infection and to report on its potential as a predictive marker.
Materials and methods: All patients, diagnosed with COVID-19 infection from February 16 to March 21, 2020, and referred to Firoozgar Hospital, Tehran, Iran, were enrolled in this study. Vitamin D analysis was undertaken on patient serum samples using a commercial kit (Pars Azmoon Co., Tehran, Iran). SPSS v. 22 was used for statistical analysis.
Results: Vitamin D serum concentration was analyzed in a total of 317 patients whose mean age ± standard deviation was 62.05 ± 15 years and with 62.5% being male. A significant association of Vitamin D level and death was observed. Higher levels of serum Vitamin D had protection against death (odds ratio = 0.955 [95% confidence interval = 0.923-0.988], P = 0.008).
Conclusion: As a preliminary study in the Iranian population who suffered COVID-19 disease, we identified that Vitamin D deficiency was associated with a higher death rate and intensive care unit admission.
Keywords: Coronavirus disease 2019; Vitamin D; malnutrition; respiratory tract infection.