tetano
Editor, Senior Moderator
J Stroke Cerebrovasc Dis
. 2021 Oct 26;31(1):106163.
doi: 10.1016/j.jstrokecerebrovasdis.2021.106163. Online ahead of print.
Hypercoagulability of COVID-19 and Neurological Complications: A Review
Patrick Moore[SUP] 1 [/SUP], Fatema Esmail[SUP] 2 [/SUP], Shuai Qin[SUP] 3 [/SUP], Sucha Nand[SUP] 4 [/SUP], Stephanie Berg[SUP] 5 [/SUP]
Affiliations
Abstract
The SARS-CoV-2 virus, which causes Coronavirus disease 2019 (COVID-19), has resulted in millions of worldwide deaths. When the SARS-CoV-2 virus emerged from Wuhan, China in December 2019, reports of patients with COVID-19 revealed that hospitalized patients had acute changes in mental status, cognition, and encephalopathy. Neurologic complications can be a consequence from overall severity of the systemic infection, direct viral invasion of the SARS-CoV-2 virus in the central nervous system, and possible immune mediated mechanisms. We will examine the landscape regarding this topic in this review in addition to current understandings of COVID-19 and hemostasis, treatment, and prevention, as well as vaccination.
Keywords: Anticoagulation; COVID-19; Neurologic outcomes; SARS-CoV-2.
. 2021 Oct 26;31(1):106163.
doi: 10.1016/j.jstrokecerebrovasdis.2021.106163. Online ahead of print.
Hypercoagulability of COVID-19 and Neurological Complications: A Review
Patrick Moore[SUP] 1 [/SUP], Fatema Esmail[SUP] 2 [/SUP], Shuai Qin[SUP] 3 [/SUP], Sucha Nand[SUP] 4 [/SUP], Stephanie Berg[SUP] 5 [/SUP]
Affiliations
- PMID: 34763262
- DOI: 10.1016/j.jstrokecerebrovasdis.2021.106163
Abstract
The SARS-CoV-2 virus, which causes Coronavirus disease 2019 (COVID-19), has resulted in millions of worldwide deaths. When the SARS-CoV-2 virus emerged from Wuhan, China in December 2019, reports of patients with COVID-19 revealed that hospitalized patients had acute changes in mental status, cognition, and encephalopathy. Neurologic complications can be a consequence from overall severity of the systemic infection, direct viral invasion of the SARS-CoV-2 virus in the central nervous system, and possible immune mediated mechanisms. We will examine the landscape regarding this topic in this review in addition to current understandings of COVID-19 and hemostasis, treatment, and prevention, as well as vaccination.
Keywords: Anticoagulation; COVID-19; Neurologic outcomes; SARS-CoV-2.