tetano
Editor, Senior Moderator
J Vasc Surg Cases Innov Tech
. 2021 Jul 23.
doi: 10.1016/j.jvscit.2021.07.006. Online ahead of print.
Acute limb ischemia and aortic mural thrombosis as primary manifestations of SARS-CoV-2
Andras Szeles[SUP] 1 [/SUP], Nayef T El-Daher[SUP] 1 [/SUP], Neil Lachant[SUP] 2 [/SUP], Toufic A Rizk[SUP] 3 [/SUP]
Affiliations
Abstract
Variable clinical presentation is emerging as a hallmark of the novel coronavirus, SARS-CoV-2. In addition to hypoxic respiratory failure, multiorgan dysfunction and septic shock, there are significant thromboembolic complications posited to be a result of diffuse coagulopathy associated with this viral infection. We report on a unique primary manifestation of SARS-CoV-2 infection presenting as acute limb ischemia and aortic mural thrombosis without clinical evidence of pulmonary disease. Despite best attempts at limb salvage with therapeutic anticoagulation, emergent aorto-iliac and distal embolectomies, the patient developed bilateral dry gangrene and ultimately required lower extremity amputations.
Keywords: aortic mural thrombus; covid; limb ischemia.
. 2021 Jul 23.
doi: 10.1016/j.jvscit.2021.07.006. Online ahead of print.
Acute limb ischemia and aortic mural thrombosis as primary manifestations of SARS-CoV-2
Andras Szeles[SUP] 1 [/SUP], Nayef T El-Daher[SUP] 1 [/SUP], Neil Lachant[SUP] 2 [/SUP], Toufic A Rizk[SUP] 3 [/SUP]
Affiliations
- PMID: 34316528
- PMCID: PMC8299151
- DOI: 10.1016/j.jvscit.2021.07.006
Abstract
Variable clinical presentation is emerging as a hallmark of the novel coronavirus, SARS-CoV-2. In addition to hypoxic respiratory failure, multiorgan dysfunction and septic shock, there are significant thromboembolic complications posited to be a result of diffuse coagulopathy associated with this viral infection. We report on a unique primary manifestation of SARS-CoV-2 infection presenting as acute limb ischemia and aortic mural thrombosis without clinical evidence of pulmonary disease. Despite best attempts at limb salvage with therapeutic anticoagulation, emergent aorto-iliac and distal embolectomies, the patient developed bilateral dry gangrene and ultimately required lower extremity amputations.
Keywords: aortic mural thrombus; covid; limb ischemia.