sharon sanders
Editor-in-Chief & President
Virucidal efficacy of different oral rinses against SARS-CoV-2
Toni Luise Meister, Yannick Br?ggemann, Daniel Todt, Carina Conzelmann, Janis A M?ller, R?diger Gro?, Jan M?nch, Adalbert Krawczyk, J?rg Steinmann, Jochen Steinmann ... Show more
Author Notes
The Journal of Infectious Diseases, jiaa471, https://doi.org/10.1093/infdis/jiaa471
Published:
29 July 2020
The ongoing SARS-CoV-2 pandemic creates a significant threat to global health. Recent studies suggested the significance of throat and salivary glands as major sites of virus replication and transmission during early COVID-19 thus advocating application of oral antiseptics. However, the antiviral efficacy of oral rinsing solutions against SARS-CoV-2 has not been examined. Here, we evaluated the virucidal activity of different available oral rinses against SARS-CoV-2 under conditions mimicking nasopharyngeal secretions.
Several formulations with significant SARS-CoV-2 inactivating properties in vitro support the idea that oral rinsing might reduce the viral load of saliva and could thus lower the transmission of SARS-CoV-2.
https://academic.oup.com/jid/advance...#.XzHYIZjze-k.
Toni Luise Meister, Yannick Br?ggemann, Daniel Todt, Carina Conzelmann, Janis A M?ller, R?diger Gro?, Jan M?nch, Adalbert Krawczyk, J?rg Steinmann, Jochen Steinmann ... Show more
Author Notes
The Journal of Infectious Diseases, jiaa471, https://doi.org/10.1093/infdis/jiaa471
Published:
29 July 2020
The ongoing SARS-CoV-2 pandemic creates a significant threat to global health. Recent studies suggested the significance of throat and salivary glands as major sites of virus replication and transmission during early COVID-19 thus advocating application of oral antiseptics. However, the antiviral efficacy of oral rinsing solutions against SARS-CoV-2 has not been examined. Here, we evaluated the virucidal activity of different available oral rinses against SARS-CoV-2 under conditions mimicking nasopharyngeal secretions.
Several formulations with significant SARS-CoV-2 inactivating properties in vitro support the idea that oral rinsing might reduce the viral load of saliva and could thus lower the transmission of SARS-CoV-2.
https://academic.oup.com/jid/advance...#.XzHYIZjze-k.