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Jpn J Infect Dis . Time to resolution of infection in COVID-19 patients: the experience of a tertiary medical center in Israel

tetano

Editor, Senior Moderator
Jpn J Infect Dis


. 2021 Aug 31.
doi: 10.7883/yoken.JJID.2021.215. Online ahead of print.
Time to resolution of infection in COVID-19 patients: the experience of a tertiary medical center in Israel


Emily Lubart[SUP] 1 2 [/SUP], Gilad Gal[SUP] 3 [/SUP], Eliyahu H Mizrahi[SUP] 1 2 [/SUP], Ahuva Tzabary[SUP] 2 [/SUP], Ehuda Baumohl[SUP] 2 [/SUP], Erica Pinco[SUP] 2 [/SUP], Zuhdi Idkiedek[SUP] 2 [/SUP], Eisa Haj Ali[SUP] 2 [/SUP], Maya Berger[SUP] 2 [/SUP], Galina Goltsman[SUP] 1 4 [/SUP]



Affiliations

Abstract

With the coronavirus disease spreading, reports indicated that young patients are usually asymptomatic with a short convalescence period. The current study compares the time to resolution of infection in symptomatic versus asymptomatic patients. Seventy- six patients aged 44.4±23.3 years were admitted to the COVID-19 Unit during the study period. Data was collected from patients' records. Throat and nasal swabs for the RT-PCR COVID-19 were collected. Time to resolution of infection was defined as the number of days from the date of the first COVID-19 positive outcome to the second consecutive negative PCR results. Most patients showed between 1-6 COVID-19 signs and symptoms (71.1%) and the rest were asymptomatic. No association was found between the time to resolution of infection and the presence of COVID-19 signs and symptoms (symptomatic: Md 10.0 95% CI 8.4-11.6; asymptomatic: Md 15.0 95% CI 10.5-15.5; p=0.54). Age was not correlated with the number of COVID-19 signs and symptoms (r=0.13, p=0.37) and with the time to resolution of infection (r=0.06, p=0.58). In mild to moderate symptomatic patients, the time to resolution of infection from COVID-19 is not different from asymptomatic patients.

Keywords: COVID-19; symptomatic vs asymptomatic patients; time to resolution of infection.
 
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