tetano
Editor, Senior Moderator
Future Microbiol. 2015 Dec 18. [Epub ahead of print]
[h=1]Knowns and unknowns of influenza B viruses.[/h] Koutsakos M[SUP]1[/SUP], Nguyen TH[SUP]1[/SUP], Barclay WS[SUP]2[/SUP], Kedzierska K[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza B viruses (IBVs) circulate annually along with influenza A (IAV) strains during seasonal epidemics. IBV can dominate influenza seasons and cause severe disease, particularly in children and adolescents. Research has revealed interesting aspects of IBV and highlighted the importance of these viruses in clinical settings. Yet, many important questions remain unanswered. In this review, the clinical relevance of IBV is emphasized, unique features in epidemiology, host range and virology are highlighted and gaps in knowledge pinpointed. Multiple aspects of IBV epidemiology, evolution, virology and immunology are discussed. Future research into IBV is needed to understand how we can prevent severe disease in high-risk groups, especially children and elderly.
[h=4]KEYWORDS:[/h] epidemiology; immunology; influenza B; virology
PMID: 26684590 [PubMed - as supplied by publisher]
[h=1]Knowns and unknowns of influenza B viruses.[/h] Koutsakos M[SUP]1[/SUP], Nguyen TH[SUP]1[/SUP], Barclay WS[SUP]2[/SUP], Kedzierska K[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza B viruses (IBVs) circulate annually along with influenza A (IAV) strains during seasonal epidemics. IBV can dominate influenza seasons and cause severe disease, particularly in children and adolescents. Research has revealed interesting aspects of IBV and highlighted the importance of these viruses in clinical settings. Yet, many important questions remain unanswered. In this review, the clinical relevance of IBV is emphasized, unique features in epidemiology, host range and virology are highlighted and gaps in knowledge pinpointed. Multiple aspects of IBV epidemiology, evolution, virology and immunology are discussed. Future research into IBV is needed to understand how we can prevent severe disease in high-risk groups, especially children and elderly.
[h=4]KEYWORDS:[/h] epidemiology; immunology; influenza B; virology
PMID: 26684590 [PubMed - as supplied by publisher]