tetano
Editor, Senior Moderator
Korean Circ J
. 2023 Sep 5.
doi: 10.4070/kcj.2023.0063. Online ahead of print. Trends and Outcomes of Type 2 Myocardial Infarction During the COVID-19 Pandemic in the United States
Harshith Thyagaturu[SUP] 1 [/SUP], Nicholas Roma[SUP] 2 [/SUP], Aakash Angirekula[SUP] 3 [/SUP], Sittinun Thangjui[SUP] 4 [/SUP], Alex Bolton[SUP] 5 [/SUP], Karthik Gonuguntla[SUP] 1 [/SUP], Yasar Sattar[SUP] 1 [/SUP], Muchi Ditah Chobufo[SUP] 1 [/SUP], Abhiram Challa[SUP] 6 [/SUP], Neel Patel[SUP] 7 [/SUP], Gayatri Bondi[SUP] 8 [/SUP], Sameer Raina[SUP] 9 [/SUP]
Affiliations
Background and objectives: There is limited data on the impact of type 2 myocardial infarction (T2MI) during the coronavirus disease 2019 (COVID-19) pandemic.
Methods: The National Inpatient Sample (NIS) database from January 2019 to December 2020 was queried to identify T2MI hospitalizations based on the appropriate International Classification of Disease, Tenth Revision-Clinical Modification codes. Monthly trends of COVID-19 and T2MI hospitalizations were evaluated using Joinpoint regression analysis. In addition, the multivariate logistic and linear regression analysis was used to compare in-hospital mortality, coronary angiography use, and resource utilization between 2019 and 2020.
Results: A total of 743,535 patients hospitalized with a diagnosis of T2MI were identified in the years 2019 (n=331,180) and 2020 (n=412,355). There was an increasing trend in T2MI hospitalizations throughout the study period corresponding to the increase in COVID-19 hospitalizations in 2020. The adjusted odds of in-hospital mortality associated with T2MI hospitalizations were significantly higher in 2020 compared with 2019 (11.1% vs. 8.1%: adjusted odds ratio, 1.19 [1.13-1.26]; p<0.01). In addition, T2MI hospitalizations were associated with lower odds of coronary angiography and higher total hospitalization charges, with no difference in the length of stay in 2020 compared with 2019.
Conclusions: We found a significant increase in T2MI hospitalizations with higher in-hospital mortality, total hospitalization costs, and lower coronary angiography use during the early COVID-19 pandemic corresponding to the trends in the rise of COVID-19 hospitalizations. Further research into the factors associated with increased mortality can increase our preparedness for future pandemics.
Keywords: COVID-19; Myocardial infarction; Myocardial ischemia; SARS-CoV-2.
. 2023 Sep 5.
doi: 10.4070/kcj.2023.0063. Online ahead of print. Trends and Outcomes of Type 2 Myocardial Infarction During the COVID-19 Pandemic in the United States
Harshith Thyagaturu[SUP] 1 [/SUP], Nicholas Roma[SUP] 2 [/SUP], Aakash Angirekula[SUP] 3 [/SUP], Sittinun Thangjui[SUP] 4 [/SUP], Alex Bolton[SUP] 5 [/SUP], Karthik Gonuguntla[SUP] 1 [/SUP], Yasar Sattar[SUP] 1 [/SUP], Muchi Ditah Chobufo[SUP] 1 [/SUP], Abhiram Challa[SUP] 6 [/SUP], Neel Patel[SUP] 7 [/SUP], Gayatri Bondi[SUP] 8 [/SUP], Sameer Raina[SUP] 9 [/SUP]
Affiliations
- PMID: 37880873
- DOI: 10.4070/kcj.2023.0063
Background and objectives: There is limited data on the impact of type 2 myocardial infarction (T2MI) during the coronavirus disease 2019 (COVID-19) pandemic.
Methods: The National Inpatient Sample (NIS) database from January 2019 to December 2020 was queried to identify T2MI hospitalizations based on the appropriate International Classification of Disease, Tenth Revision-Clinical Modification codes. Monthly trends of COVID-19 and T2MI hospitalizations were evaluated using Joinpoint regression analysis. In addition, the multivariate logistic and linear regression analysis was used to compare in-hospital mortality, coronary angiography use, and resource utilization between 2019 and 2020.
Results: A total of 743,535 patients hospitalized with a diagnosis of T2MI were identified in the years 2019 (n=331,180) and 2020 (n=412,355). There was an increasing trend in T2MI hospitalizations throughout the study period corresponding to the increase in COVID-19 hospitalizations in 2020. The adjusted odds of in-hospital mortality associated with T2MI hospitalizations were significantly higher in 2020 compared with 2019 (11.1% vs. 8.1%: adjusted odds ratio, 1.19 [1.13-1.26]; p<0.01). In addition, T2MI hospitalizations were associated with lower odds of coronary angiography and higher total hospitalization charges, with no difference in the length of stay in 2020 compared with 2019.
Conclusions: We found a significant increase in T2MI hospitalizations with higher in-hospital mortality, total hospitalization costs, and lower coronary angiography use during the early COVID-19 pandemic corresponding to the trends in the rise of COVID-19 hospitalizations. Further research into the factors associated with increased mortality can increase our preparedness for future pandemics.
Keywords: COVID-19; Myocardial infarction; Myocardial ischemia; SARS-CoV-2.