tetano
Editor, Senior Moderator
Lancet Infect Dis
. 2024 Aug 9:S1473-3099(24)00438-9.
doi: 10.1016/S1473-3099(24)00438-9. Online ahead of print. The panzootic spread of highly pathogenic avian influenza H5N1 sublineage 2.3.4.4b: a critical appraisal of One Health preparedness and prevention
Marion P G Koopmans[SUP] 1 [/SUP], Casey Barton Behravesh[SUP] 2 [/SUP], Andrew A Cunningham[SUP] 3 [/SUP], Wiku B Adisasmito[SUP] 4 [/SUP], Salama Almuhairi[SUP] 5 [/SUP], Pépé Bilivogui[SUP] 6 [/SUP], Salome A Bukachi[SUP] 7 [/SUP], Natalia Casas[SUP] 8 [/SUP], Natalia Cediel Becerra[SUP] 9 [/SUP], Dominique F Charron[SUP] 10 [/SUP], Abhishek Chaudhary[SUP] 11 [/SUP], Janice R Ciacci Zanella[SUP] 12 [/SUP], Osman Dar[SUP] 13 [/SUP], Nitish Debnath[SUP] 14 [/SUP], Baptiste Dungu[SUP] 15 [/SUP], Elmoubasher Farag[SUP] 16 [/SUP], George F Gao[SUP] 17 [/SUP], Margaret Khaitsa[SUP] 18 [/SUP], Catherine Machalaba[SUP] 19 [/SUP], John S Mackenzie[SUP] 20 [/SUP], Wanda Markotter[SUP] 21 [/SUP], Thomas C Mettenleiter[SUP] 22 [/SUP], Serge Morand[SUP] 23 [/SUP], Vyacheslav Smolenskiy[SUP] 24 [/SUP], Lei Zhou[SUP] 25 [/SUP], David T S Hayman[SUP] 26 [/SUP]; One Health High-Level Expert Panel
Affiliations
Changes in the epidemiology and ecology of H5N1 highly pathogenic avian influenza are devastating wild bird and poultry populations, farms and communities, and wild mammals worldwide. Having originated in farmed poultry, H5N1 viruses are now spread globally by wild birds, with transmission to many mammal and avian species, resulting in 2024 in transmission among dairy cattle with associated human cases. These ecological changes pose challenges to mitigating the impacts of H5N1 highly pathogenic avian influenza on wildlife, ecosystems, domestic animals, food security, and humans. H5N1 highly pathogenic avian influenza highlights the need for One Health approaches to pandemic prevention and preparedness, emphasising multisectoral collaborations among animal, environmental, and public health sectors. Action is needed to reduce future pandemic risks by preventing transmission of highly pathogenic avian influenza among domestic and wild animals and people, focusing on upstream drivers of outbreaks, and ensuring rapid responses and risk assessments for zoonotic outbreaks. Political commitment and sustainable funding are crucial to implementing and maintaining prevention programmes, surveillance, and outbreak responses.
. 2024 Aug 9:S1473-3099(24)00438-9.
doi: 10.1016/S1473-3099(24)00438-9. Online ahead of print. The panzootic spread of highly pathogenic avian influenza H5N1 sublineage 2.3.4.4b: a critical appraisal of One Health preparedness and prevention
Marion P G Koopmans[SUP] 1 [/SUP], Casey Barton Behravesh[SUP] 2 [/SUP], Andrew A Cunningham[SUP] 3 [/SUP], Wiku B Adisasmito[SUP] 4 [/SUP], Salama Almuhairi[SUP] 5 [/SUP], Pépé Bilivogui[SUP] 6 [/SUP], Salome A Bukachi[SUP] 7 [/SUP], Natalia Casas[SUP] 8 [/SUP], Natalia Cediel Becerra[SUP] 9 [/SUP], Dominique F Charron[SUP] 10 [/SUP], Abhishek Chaudhary[SUP] 11 [/SUP], Janice R Ciacci Zanella[SUP] 12 [/SUP], Osman Dar[SUP] 13 [/SUP], Nitish Debnath[SUP] 14 [/SUP], Baptiste Dungu[SUP] 15 [/SUP], Elmoubasher Farag[SUP] 16 [/SUP], George F Gao[SUP] 17 [/SUP], Margaret Khaitsa[SUP] 18 [/SUP], Catherine Machalaba[SUP] 19 [/SUP], John S Mackenzie[SUP] 20 [/SUP], Wanda Markotter[SUP] 21 [/SUP], Thomas C Mettenleiter[SUP] 22 [/SUP], Serge Morand[SUP] 23 [/SUP], Vyacheslav Smolenskiy[SUP] 24 [/SUP], Lei Zhou[SUP] 25 [/SUP], David T S Hayman[SUP] 26 [/SUP]; One Health High-Level Expert Panel
Affiliations
- PMID: 39134084
- DOI: 10.1016/S1473-3099(24)00438-9
Changes in the epidemiology and ecology of H5N1 highly pathogenic avian influenza are devastating wild bird and poultry populations, farms and communities, and wild mammals worldwide. Having originated in farmed poultry, H5N1 viruses are now spread globally by wild birds, with transmission to many mammal and avian species, resulting in 2024 in transmission among dairy cattle with associated human cases. These ecological changes pose challenges to mitigating the impacts of H5N1 highly pathogenic avian influenza on wildlife, ecosystems, domestic animals, food security, and humans. H5N1 highly pathogenic avian influenza highlights the need for One Health approaches to pandemic prevention and preparedness, emphasising multisectoral collaborations among animal, environmental, and public health sectors. Action is needed to reduce future pandemic risks by preventing transmission of highly pathogenic avian influenza among domestic and wild animals and people, focusing on upstream drivers of outbreaks, and ensuring rapid responses and risk assessments for zoonotic outbreaks. Political commitment and sustainable funding are crucial to implementing and maintaining prevention programmes, surveillance, and outbreak responses.