tetano
Editor, Senior Moderator
Leukemia
. 2020 Jul 20.
doi: 10.1038/s41375-020-0986-7. Online ahead of print.
Cancer increases risk of in-hospital death from COVID-19 in persons <65 years and those not in complete remission
Qiubai Li[SUP] 1 [/SUP], Lei Chen[SUP] 2 [/SUP], Qin Li[SUP] 3 [/SUP], Wenjuan He[SUP] 2 [/SUP], Jianming Yu[SUP] 2 [/SUP], Li Chen[SUP] 4 [/SUP], Yulin Cao[SUP] 2 [/SUP], Wenlan Chen[SUP] 2 [/SUP], Di Wu[SUP] 2 [/SUP], Fang Dong[SUP] 5 [/SUP], Liling Cai[SUP] 6 [/SUP], Qijie Ran[SUP] 7 [/SUP], Lei Li[SUP] 8 [/SUP], Qiaomei Liu[SUP] 9 [/SUP], Wenxiang Ren[SUP] 2 [/SUP], Fei Gao[SUP] 2 [/SUP], Hongxiang Wang[SUP] 4 [/SUP], Zhichao Chen[SUP] 2 [/SUP], Robert Peter Gale[SUP] 10 [/SUP], Yu Hu[SUP] 11 [/SUP]
Affiliations
Abstract
The impact of cancer on outcome of persons with coronavirus disease 2019 (COVID-19) after infection with acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is controversial. We studied 1859 subjects with COVID-19 from seven centers in Wuhan, China, 65 of whom had cancer. We found having cancer was an independent risk factor for in-hospital death from COVID-19 in persons <65 years (hazard ratio
= 2.45, 95% confidence interval [CI], 1.04, 5.76; P = 0.041) but not in those ≥65 years (HR = 1.12 [0.56, 2.24]; P = 0.740). It was also more common in those not in complete remission. Risks of in-hospital death were similar in subjects with solid cancers and those with hematological cancers. These data may help predict outcomes of persons with cancer and COVID-19.
. 2020 Jul 20.
doi: 10.1038/s41375-020-0986-7. Online ahead of print.
Cancer increases risk of in-hospital death from COVID-19 in persons <65 years and those not in complete remission
Qiubai Li[SUP] 1 [/SUP], Lei Chen[SUP] 2 [/SUP], Qin Li[SUP] 3 [/SUP], Wenjuan He[SUP] 2 [/SUP], Jianming Yu[SUP] 2 [/SUP], Li Chen[SUP] 4 [/SUP], Yulin Cao[SUP] 2 [/SUP], Wenlan Chen[SUP] 2 [/SUP], Di Wu[SUP] 2 [/SUP], Fang Dong[SUP] 5 [/SUP], Liling Cai[SUP] 6 [/SUP], Qijie Ran[SUP] 7 [/SUP], Lei Li[SUP] 8 [/SUP], Qiaomei Liu[SUP] 9 [/SUP], Wenxiang Ren[SUP] 2 [/SUP], Fei Gao[SUP] 2 [/SUP], Hongxiang Wang[SUP] 4 [/SUP], Zhichao Chen[SUP] 2 [/SUP], Robert Peter Gale[SUP] 10 [/SUP], Yu Hu[SUP] 11 [/SUP]
Affiliations
- PMID: 32690880
- DOI: 10.1038/s41375-020-0986-7
Abstract
The impact of cancer on outcome of persons with coronavirus disease 2019 (COVID-19) after infection with acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is controversial. We studied 1859 subjects with COVID-19 from seven centers in Wuhan, China, 65 of whom had cancer. We found having cancer was an independent risk factor for in-hospital death from COVID-19 in persons <65 years (hazard ratio
= 2.45, 95% confidence interval [CI], 1.04, 5.76; P = 0.041) but not in those ≥65 years (HR = 1.12 [0.56, 2.24]; P = 0.740). It was also more common in those not in complete remission. Risks of in-hospital death were similar in subjects with solid cancers and those with hematological cancers. These data may help predict outcomes of persons with cancer and COVID-19.