tetano
Editor, Senior Moderator
Arch Neurol. 2010 Aug;67(8):1018-20.
Longitudinally Extensive Transverse Myelitis Following Vaccination With Nasal Attenuated Novel Influenza A(H1N1) Vaccine.
Akkad W, Salem B, Freeman JW, Huntington MK.
Center for Family Medicine, 1115 E 20th St, Sioux Falls, SD 57105. mark.huntington@usd.edu.
Abstract
BACKGROUND: Transverse myelitis has been reported in association with vaccination, including influenza vaccination. OBJECTIVE: To describe a case of longitudinally extensive transverse myelitis associated with vaccination with a nasal attenuated novel influenza A(H1N1) vaccine. DESIGN: Case report. SETTING: Sanford University of South Dakota Hospital. Patient A 27-year-old woman with longitudinally extensive transverse myelitis. RESULTS: Four days following novel influenza A(H1N1) vaccination, the patient developed longitudinally extensive transverse myelitis. Extensive diagnostic evaluation effectively ruled out causes other than vaccination-associated transverse myelitis. Following treatment with corticosteroids and plasmapheresis, the patient made a significant recovery. CONCLUSIONS: Transverse myelitis may be associated with vaccination against novel influenza A(H1N1). Additionally, we believe this to be the first report of longitudinally extensive transverse myelitis associated with any vaccine.
PMID: 20697056 [PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/20697056
Longitudinally Extensive Transverse Myelitis Following Vaccination With Nasal Attenuated Novel Influenza A(H1N1) Vaccine.
Akkad W, Salem B, Freeman JW, Huntington MK.
Center for Family Medicine, 1115 E 20th St, Sioux Falls, SD 57105. mark.huntington@usd.edu.
Abstract
BACKGROUND: Transverse myelitis has been reported in association with vaccination, including influenza vaccination. OBJECTIVE: To describe a case of longitudinally extensive transverse myelitis associated with vaccination with a nasal attenuated novel influenza A(H1N1) vaccine. DESIGN: Case report. SETTING: Sanford University of South Dakota Hospital. Patient A 27-year-old woman with longitudinally extensive transverse myelitis. RESULTS: Four days following novel influenza A(H1N1) vaccination, the patient developed longitudinally extensive transverse myelitis. Extensive diagnostic evaluation effectively ruled out causes other than vaccination-associated transverse myelitis. Following treatment with corticosteroids and plasmapheresis, the patient made a significant recovery. CONCLUSIONS: Transverse myelitis may be associated with vaccination against novel influenza A(H1N1). Additionally, we believe this to be the first report of longitudinally extensive transverse myelitis associated with any vaccine.
PMID: 20697056 [PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/20697056