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Source: https://www.livescience.com/measles-wipes-immune-memory.html
Measles Wipes Your Immune System's 'Memory,' So It Can't Fight Other Infections
By Nicoletta Lanese - Staff Writer 4 hours ago Health
Two new studies detail how the measles virus causes "immune amnesia."
The notorious measles virus not only makes people sick, it also sneaks inside important immune cells in the body and wipes their "memories," new research suggests.
Once infected, the amnesic immune system no longer recognizes the harmful pathogens that it has fought off in the past. This means measles survivors can remain susceptible to dangerous diseases — such as the flu and pneumonia — for years to come, despite having weathered their initial illness.
"Measles essentially takes away their ability to efficiently protect themselves," said Michael Mina, an epidemiologist at Harvard University and co-author of the new study, published today (Oct. 31) in the journal Science. The paper pairs with another published today in Science Immunology. Using data from a group of unvaccinated children in the Netherlands, both studies revealed what scientists have long suspected: that the measles virus cripples the immune system in a profound and lasting way.
"What this has done is document exactly how that immunosuppression takes place, and gives us a sense of how broad that immunosuppression can be," said Dr. William Schaffner, a professor of preventive medicine and infectious disease at Vanderbilt University who was not involved in the work. The findings also serve as a reminder that this year's record-breaking measles outbreaks in the U.S. will have lingering effects, Schaffner added...
Measles Wipes Your Immune System's 'Memory,' So It Can't Fight Other Infections
By Nicoletta Lanese - Staff Writer 4 hours ago Health
Two new studies detail how the measles virus causes "immune amnesia."
The notorious measles virus not only makes people sick, it also sneaks inside important immune cells in the body and wipes their "memories," new research suggests.
Once infected, the amnesic immune system no longer recognizes the harmful pathogens that it has fought off in the past. This means measles survivors can remain susceptible to dangerous diseases — such as the flu and pneumonia — for years to come, despite having weathered their initial illness.
"Measles essentially takes away their ability to efficiently protect themselves," said Michael Mina, an epidemiologist at Harvard University and co-author of the new study, published today (Oct. 31) in the journal Science. The paper pairs with another published today in Science Immunology. Using data from a group of unvaccinated children in the Netherlands, both studies revealed what scientists have long suspected: that the measles virus cripples the immune system in a profound and lasting way.
"What this has done is document exactly how that immunosuppression takes place, and gives us a sense of how broad that immunosuppression can be," said Dr. William Schaffner, a professor of preventive medicine and infectious disease at Vanderbilt University who was not involved in the work. The findings also serve as a reminder that this year's record-breaking measles outbreaks in the U.S. will have lingering effects, Schaffner added...