tetano
Editor, Senior Moderator
MedComm (2020)
. 2024 Jul 14;5(7):e655.
doi: 10.1002/mco2.655. eCollection 2024 Jul. Risk of pulmonary embolism and deep vein thrombosis following COVID-19: a nationwide cohort study
Hye Jun Kim[SUP] 1 [/SUP], Seogsong Jeong[SUP] 2 [/SUP], Jihun Song[SUP] 1 [/SUP], Sun Jae Park[SUP] 1 [/SUP], Young Jun Park[SUP] 3 [/SUP], Yun Hwan Oh[SUP] 4 [/SUP], Jaehun Jung[SUP] 5 [/SUP], Sang Min Park[SUP] 1 6 [/SUP]
Affiliations
Recent studies elucidate that coronavirus disease 2019 (COVID-19) patients may face a higher risk of cardiovascular complications. This study aimed to evaluate association of COVID-19 with the risk of pulmonary embolism (PE) or deep vein thrombosis (DVT). This nationwide population-based retrospective cohort study included Korean adult citizens between January 2021 and March 2022 from the Korea Disease Control and Prevention Agency COVID-19 National Health Insurance Service cohort. The Fine and Gray's regression with all-cause death as a competing event was adopted to evaluate PE and DVT risks after COVID-19. This study included a total of 1,601,835 COVID-19 patients and 14,011,285 matched individuals without COVID-19. The risk of PE (adjusted hazard ratio [aHR], 6.25; 95% confidence interval [CI], 3.67-10.66; p < 0.001) and DVT (aHR, 3.05; 95% CI, 1.75-5.29; p < 0.001) was higher in COVID-19 group in individuals without complete COVID-19 vaccination. In addition, individuals with complete COVID-19 vaccination still had a higher risk of COVID-19-related PE (aHR, 1.48; 95% CI, 1.15-1.88; p < 0.001). However, COVID-19 was not a significant risk factor for DVT among those with complete COVID-19 vaccination. COVID-19 was identified as an independent factor that elevated PE and DVT risks, especially for individuals without complete COVID-19 vaccination.
Keywords: SARS‐CoV‐2; embolism; long‐term sequelae; postacute COVID‐19 syndrome; thrombosis.
. 2024 Jul 14;5(7):e655.
doi: 10.1002/mco2.655. eCollection 2024 Jul. Risk of pulmonary embolism and deep vein thrombosis following COVID-19: a nationwide cohort study
Hye Jun Kim[SUP] 1 [/SUP], Seogsong Jeong[SUP] 2 [/SUP], Jihun Song[SUP] 1 [/SUP], Sun Jae Park[SUP] 1 [/SUP], Young Jun Park[SUP] 3 [/SUP], Yun Hwan Oh[SUP] 4 [/SUP], Jaehun Jung[SUP] 5 [/SUP], Sang Min Park[SUP] 1 6 [/SUP]
Affiliations
- PMID: 39006761
- PMCID: PMC11246596
- DOI: 10.1002/mco2.655
Recent studies elucidate that coronavirus disease 2019 (COVID-19) patients may face a higher risk of cardiovascular complications. This study aimed to evaluate association of COVID-19 with the risk of pulmonary embolism (PE) or deep vein thrombosis (DVT). This nationwide population-based retrospective cohort study included Korean adult citizens between January 2021 and March 2022 from the Korea Disease Control and Prevention Agency COVID-19 National Health Insurance Service cohort. The Fine and Gray's regression with all-cause death as a competing event was adopted to evaluate PE and DVT risks after COVID-19. This study included a total of 1,601,835 COVID-19 patients and 14,011,285 matched individuals without COVID-19. The risk of PE (adjusted hazard ratio [aHR], 6.25; 95% confidence interval [CI], 3.67-10.66; p < 0.001) and DVT (aHR, 3.05; 95% CI, 1.75-5.29; p < 0.001) was higher in COVID-19 group in individuals without complete COVID-19 vaccination. In addition, individuals with complete COVID-19 vaccination still had a higher risk of COVID-19-related PE (aHR, 1.48; 95% CI, 1.15-1.88; p < 0.001). However, COVID-19 was not a significant risk factor for DVT among those with complete COVID-19 vaccination. COVID-19 was identified as an independent factor that elevated PE and DVT risks, especially for individuals without complete COVID-19 vaccination.
Keywords: SARS‐CoV‐2; embolism; long‐term sequelae; postacute COVID‐19 syndrome; thrombosis.