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Medicine (Baltimore) . Comparison of clinical, laboratory, and radiological characteristics between SARS-CoV-2 infection and community-acquired pne

tetano

Editor, Senior Moderator
Medicine (Baltimore)


. 2020 Oct 30;99(44):e23064.
doi: 10.1097/MD.0000000000023064.
Comparison of clinical, laboratory, and radiological characteristics between SARS-CoV-2 infection and community-acquired pneumonia caused by influenza virus: A cross-sectional retrospective study


Yi-Hua Lin[SUP] 1 2 [/SUP], Wen Luo[SUP] 1 [/SUP], Ding-Hui Wu[SUP] 3 [/SUP], Fang Lu[SUP] 1 [/SUP], Su-Xian Hu[SUP] 1 [/SUP], Xiang-Yang Yao[SUP] 3 [/SUP], Zhan-Xiang Wang[SUP] 2 4 [/SUP], Yong-Hong Shi[SUP] 1 2 [/SUP]



Affiliations

Abstract

Coronavirus disease 2019 (COVID-19) is the most important global public health issue that we currently face. We aimed to explore the clinical features of patients with COVID-19 and compared them with those of hospitalized community-acquired pneumonia (CAP) patients caused by influenza virus during the same period.From Jan 1, to Mar 4, 2020, patients with COVID-19 or CAP caused by influenza virus who were admitted to the First Affiliated Hospital of Xiamen University were consecutively screened for enrollment.A total of 35 COVID-19 patients and 22 CAP patients caused by influenza virus were included in this study. Most of COVID-19 patients had characteristics of familial clustering (63%), however, in the other group, there was no similar finding. The percentages of patients with a high fever (the highest recorded temperature was ≥39.0?C; 11% vs 45% [COVID-19 vs CAP groups, respectively]), dyspnea (9% vs 59%), leukocytosis (3% vs 32%), elevated C-reactive protein concentrations (>10 mg/L, 48% vs 86%), elevated procalcitonin levels (>0.1 ng/ml, 15% vs 73%), PaO2/FiO2 <200 mm Hg (4% vs 22%), and infiltration on imaging (29% vs 68%) in the COVID-19 group were less than those same indices in the hospitalized CAP patients caused by influenza virus. Ground-glass opacity with reticular pattern (63%) and interlobular septal thickening (71%) in chest CT were commonly observed in the COVID-19 group.COVID-19 and CAP caused by influenza virus appear to share some similarities in clinical manifestaions but they definitely have major distinctions. Influenza infection remains a health problem even during COVID-19 pandemic.
 
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