tetano
Editor, Senior Moderator
Medicine (Baltimore)
. 2020 Jul 31;99(31):e21597.
doi: 10.1097/MD.0000000000021597.
Therapeutic response to corticosteroids in a critically ill patient with COVID-19: A case report
Kaige Wang[SUP] 1 [/SUP], Fen Tan[SUP] 2 [/SUP], Rui Zhou[SUP] 2 [/SUP], Dan Liu[SUP] 1 [/SUP], Zhong Ni[SUP] 1 [/SUP], Jiasheng Liu[SUP] 3 [/SUP], Fengming Luo[SUP] 1 [/SUP]
Affiliations
Abstract
Introduction: Since the coronavirus disease 2019 (COVID-19) outbreak in Wuhan in late 2019, controversy on the use of corticosteroids for COVID-19 has obtained increasing attention. We present 1 critically ill patient who had a rapid therapeutic response to moderate-dose corticosteroids.
Patient concerns: A 53-year-old critically ill woman from Wuhan suffered with COVID-19.
Diagnosis: The chest computed tomography scan was suggestive of COVID-19. The diagnosis was confirmed by a real-time reverse transcription polymerase chain reaction test for SARS-CoV-2. The critically ill status was characterized by worsening dyspnea, progressing bilateral lung consolidation, and poor oxygenation (SiO2/FiO2:110 mm Hg).
Interventions: The patient was treated with a moderate dose of intravenous corticosteroids and high-flow nasal cannula oxygen therapy.
Outcomes: After the initiation of corticosteroids, the patient rapidly improved over the following 6 days. Serial chest computed tomography scans showed good absorption of the consolidations. The patient was discharged on Day 17 of hospitalization without obvious adverse effects.
Conclusions: Early use of moderate-dose corticosteroids over a short period may enhance recovery from COVID-19 in critically ill patients.
. 2020 Jul 31;99(31):e21597.
doi: 10.1097/MD.0000000000021597.
Therapeutic response to corticosteroids in a critically ill patient with COVID-19: A case report
Kaige Wang[SUP] 1 [/SUP], Fen Tan[SUP] 2 [/SUP], Rui Zhou[SUP] 2 [/SUP], Dan Liu[SUP] 1 [/SUP], Zhong Ni[SUP] 1 [/SUP], Jiasheng Liu[SUP] 3 [/SUP], Fengming Luo[SUP] 1 [/SUP]
Affiliations
- PMID: 32756215
- DOI: 10.1097/MD.0000000000021597
Abstract
Introduction: Since the coronavirus disease 2019 (COVID-19) outbreak in Wuhan in late 2019, controversy on the use of corticosteroids for COVID-19 has obtained increasing attention. We present 1 critically ill patient who had a rapid therapeutic response to moderate-dose corticosteroids.
Patient concerns: A 53-year-old critically ill woman from Wuhan suffered with COVID-19.
Diagnosis: The chest computed tomography scan was suggestive of COVID-19. The diagnosis was confirmed by a real-time reverse transcription polymerase chain reaction test for SARS-CoV-2. The critically ill status was characterized by worsening dyspnea, progressing bilateral lung consolidation, and poor oxygenation (SiO2/FiO2:110 mm Hg).
Interventions: The patient was treated with a moderate dose of intravenous corticosteroids and high-flow nasal cannula oxygen therapy.
Outcomes: After the initiation of corticosteroids, the patient rapidly improved over the following 6 days. Serial chest computed tomography scans showed good absorption of the consolidations. The patient was discharged on Day 17 of hospitalization without obvious adverse effects.
Conclusions: Early use of moderate-dose corticosteroids over a short period may enhance recovery from COVID-19 in critically ill patients.