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Microbiol Spectr . Lymphocyte and neutrophil count combined with intestinal bacteria abundance predict the severity of COVID-19

tetano

tetano

Editor, Senior Moderator
Microbiol Spectr


. 2023 Dec 13:e0302723.
doi: 10.1128/spectrum.03027-23. Online ahead of print. Lymphocyte and neutrophil count combined with intestinal bacteria abundance predict the severity of COVID-19

Liuying Chen[SUP] #[/SUP][SUP] 1 [/SUP], Zhongwei Yin[SUP] #[/SUP][SUP] 2 [/SUP], Dan Zhou[SUP] 1 [/SUP], Xin Li[SUP] 3 [/SUP], Cheng Yu[SUP] 4 [/SUP], Chang Luo[SUP] 1 [/SUP], Yu Jin[SUP] 1 [/SUP], Lei Zhang[SUP] 1 [/SUP], Jun Song[SUP] 1 [/SUP], Leo Rasche[SUP] 5 [/SUP], Hermann Einsele[SUP] 5 [/SUP], Lei Tu[SUP] 1 [/SUP], Xiang Zhou[SUP] 5 [/SUP], Tao Bai[SUP] 1 [/SUP], Xiaohua Hou[SUP] 1 [/SUP]



Affiliations
Abstract

The 2019 coronavirus disease (COVID-19) patients had a unique profile of gut bacteria. In this study, we characterized the intestinal bacteria in our COVID-19 cohorts and found that there was an increased incidence of severe cases in COVID-19 patients with decreased lymphocytes and increased neutrophils. Levels of lymphocytes and neutrophils and abundances of intestinal bacteria correlated with the severity of COVID-19.

Keywords: COVID-19; bacteria; lymphocytes; neutrophils.

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